1400W dihydrochloride

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Names

[ CAS No. ]:
214358-33-5

[ Name ]:
1400W dihydrochloride

[Synonym ]:
(1E)-N'-[3-(Aminomethyl)benzyl]ethanimidamide dihydrochloride
1400 W dihydrochloride
MFCD03428622
Ethanimidamide, N'-[[3-(aminomethyl)phenyl]methyl]-, (1E)-, hydrochloride (1:2)
1400W dihydrochloride
1400W (Dihydrochloride)

Chemical & Physical Properties

[ Boiling Point ]:
329ºC at 760 mmHg

[ Molecular Formula ]:
C10H17Cl2N3

[ Molecular Weight ]:
250.168

[ Flash Point ]:
152.7ºC

[ Exact Mass ]:
249.079956

[ PSA ]:
61.90000

[ LogP ]:
4.02700

[ Vapour Pressure ]:
0.000183mmHg at 25°C

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

NOS1-dependent negative feedback regulation of the epithelial sodium channel in the collecting duct.

Am. J. Physiol. Renal Physiol. 308(3) , F244-51, (2015)

With an increase in urine flow there is a significant increase in shear stress against the renal epithelium including the inner medullary collecting duct, resulting in an increase in nitric oxide (NO)...

Gardenamide A Protects RGC-5 Cells from H₂O₂-Induced Oxidative Stress Insults by Activating PI3K/Akt/eNOS Signaling Pathway.

Int. J. Mol. Sci. 16 , 22350-67, (2015)

Gardenamide A (GA) protects the rat retinal ganglion (RGC-5) cells against cell apoptosis induced by H₂O₂. The protective effect of GA was completely abrogated by the specific phosphoinositide 3-kinas...

Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor.

Cancer Res. 57 , 3300, (1997)

We have investigated the effect of N-(3-(aminomethyl)benzyl)acetamidine (1400W), a novel and highly selective inhibitor for inducible NOS (iNOS), on in vivo growth of solid tumors expressing iNOS. For...


More Articles

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