Imatinib Mesylate (STI571)

Suppliers

Names

[ CAS No. ]:
220127-57-1

[ Name ]:
Imatinib Mesylate (STI571)

[Synonym ]:
4-[(4-Methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide methanesulfonate
MFCD04307699
Imatinib mesylate
Benzamide, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-, methanesulfonate (1:1)
Imatinib mesilate (JAN)
Methansulfonsäure--4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzolcarboxamid(1:1)
4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide methanesulfonate
Imantinib mesylate
4-[(4-Methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide methanesulfonate (1:1)
Gleevac
GLEEVEC
Imatinib mesilate
4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide methanesulfonate (1:1)
Glivec
STI-571

Chemical & Physical Properties

[ Density]:
0.858 g/mL at 25 °C(lit.)

[ Boiling Point ]:
133-134 °C(lit.)

[ Melting Point ]:
214-224°C

[ Molecular Formula ]:
C₃₀H₃₅N₇O₄S

[ Molecular Weight ]:
589.708

[ Flash Point ]:
64°F

[ Exact Mass ]:
589.247131

[ PSA ]:
149.03000

[ LogP ]:
5.19690

[ Index of Refraction ]:
n20/D 1.401(lit.)

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ Safety Phrases ]:
S16-S26-S36/37/39

[ RIDADR ]:
UN 1993 3/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Paradoxical and contradictory effects of imatinib in two cell line models of hormone-refractory prostate cancer.

Prostate 75 , 923-35, (2015)

Imatinib mesylate is a chemotherapeutic drug that inhibits the tyrosine kinase activity of c-KIT and has been successfully used to treat leukemias and some solid tumors. However, its application for t...

Evaluation of the toxic effects of four anti-cancer drugs in plant bioassays and its potency for screening in the context of waste water reuse for irrigation.

Chemosphere 135 , 403-10, (2015)

Anti-cancer drugs are compounds that are of high environmental relevance because of their lack of specific mode of action. They can be extremely harmful to living organisms even at low concentrations....

Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain.

Glia 64 , 122-38, (2016)

Transcription factors of the SoxD protein family have previously been shown to prevent precocious specification and terminal differentiation of oligodendrocyte progenitor cells in the developing spina...