Imatinib Mesylate (STI571)
Imatinib Mesylate (STI571) structure
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Common Name | Imatinib Mesylate (STI571) | ||
|---|---|---|---|---|
| CAS Number | 220127-57-1 | Molecular Weight | 589.708 | |
| Density | 0.858 g/mL at 25 °C(lit.) | Boiling Point | 133-134 °C(lit.) | |
| Molecular Formula | C30H35N7O4S | Melting Point | 214-224°C | |
| MSDS | Chinese USA | Flash Point | 64°F | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Paradoxical and contradictory effects of imatinib in two cell line models of hormone-refractory prostate cancer.
Prostate 75 , 923-35, (2015) Imatinib mesylate is a chemotherapeutic drug that inhibits the tyrosine kinase activity of c-KIT and has been successfully used to treat leukemias and some solid tumors. However, its application for treatment of hormone-refractory prostate cancer (HRPC) has s... |
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Evaluation of the toxic effects of four anti-cancer drugs in plant bioassays and its potency for screening in the context of waste water reuse for irrigation.
Chemosphere 135 , 403-10, (2015) Anti-cancer drugs are compounds that are of high environmental relevance because of their lack of specific mode of action. They can be extremely harmful to living organisms even at low concentrations. The present study evaluated the toxic effects of four freq... |
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Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain.
Glia 64 , 122-38, (2016) Transcription factors of the SoxD protein family have previously been shown to prevent precocious specification and terminal differentiation of oligodendrocyte progenitor cells in the developing spinal cord. Using mice with specific deletion of the SoxD prote... |