LFM-A13

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
487.9±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₈Br₂N₂O₂

[ Molecular Weight ]:
360.001

[ Flash Point ]:
248.9±28.7 °C

[ Exact Mass ]:
357.895233

[ PSA ]:
73.12000

[ LogP ]:
3.42

[ Appearance of Characters ]:
powder | white

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.677

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMSO: 15 mg/mL

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
20/21/22

[ Safety Phrases ]:
36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Click to get detail synthetic route

Precursor

DownStream

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.

EMBO Mol. Med. 7(3) , 240-58, (2015)

Transplant recipients on calcineurin inhibitors are at high risk of invasive fungal infection. Understanding how calcineurin inhibitors impair fungal immunity is a key priority for defining risk of in...

Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells.

Mol. Cancer 9 , 267, (2010)

Recently, much attention has been focused on gaining a better understanding of the different populations of cells within a tumor and their contribution to cancer progression. One of the most commonly ...

Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung.

J. Exp. Med. 206(4) , 937-52, (2009)

Differentiation and recruitment of alternatively activated macrophages (AAMacs) are hallmarks of several inflammatory conditions associated with infection, allergy, diabetes, and cancer. AAMacs are de...

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