DPO-1

Suppliers

Names

[ CAS No. ]:
43077-30-1

[ Name ]:
DPO-1

[Synonym ]:
DPO-1
HMS3269O11
neomenthyldiphenylphosphine oxide
Neomenthyldiphenylphosphin-oxid
HMS3261N07

Chemical & Physical Properties

[ Density]:
1.054g/cm3

[ Boiling Point ]:
434.966ºC at 760 mmHg

[ Molecular Formula ]:
C22H29OP

[ Molecular Weight ]:
340.43900

[ Flash Point ]:
216.86ºC

[ Exact Mass ]:
340.19600

[ PSA ]:
26.88000

[ LogP ]:
5.46130

[ Index of Refraction ]:
1.547

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2902909090

Synthetic Route

Precursor & DownStream

Precursor

  • Diphenylphosphine oxide
  • (-)-Menthyl Chloride
  • Triphenylphosphine
  • L-Menthol

DownStream

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Articles

Polycomb-dependent repression of the potassium channel-encoding gene KCNA5 promotes cancer cell survival under conditions of stress.

Oncogene 34 , 4591-600, (2015)

Relapse after clinical remission remains a leading cause of cancer-associated death. Although the mechanisms of tumor relapse are complex, the ability of cancer cells to survive physiological stress i...

HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction.

Cardiovasc. Res. 109 , 115-30, (2015)

Hypoxic conditions stimulate pulmonary vasoconstriction and vascular remodelling, both pathognomonic changes in pulmonary arterial hypertension (PAH). The secreted protein thrombospondin-1 (TSP1) is i...

Potent suppression of Kv1.3 potassium channel and IL-2 secretion by diphenyl phosphine oxide-1 in human T cells.

PLoS ONE 8 , e64629, (2013)

Diphenyl phosphine oxide-1 (DPO-1) is a potent Kv1.5 channel inhibitor that has therapeutic potential for the treatment of atrial fibrillation. Many other Kv1.5 channel blockers also potently inhibit ...


More Articles


Related Compounds

  • Propane,1,1-bis(ethylsulfonyl)-2-methyl-
  • Pyridinium, 1- (2-hydroxy[1,1:3,1-terphenyl]-5-yl)-2,4, 6-triphenyl-, perchlorate (salt)
  • Cyclohexanecarboxylicacid, 1-methyl-3-oxo-, ethyl ester
  • 2-[1-(2-hydroxy-3,5-dimethylphenyl)cyclohexyl]-4,6-dimethylphenol
  • 3-[1-(2,5-dimethylthiophen-3-yl)octadecyl]-4-propan-2-ylideneoxolane-2,5-dione
  • trans-1,2-Dimethylcyclohexane
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-(4-((3-(2,2,2-trifluoroethoxy)azetidin-1-yl)sulfonyl)phenyl)-1H-pyrazole
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2,2-Difluoro-1-(2-fluoro-5-nitrophenyl)ethan-1-one
  • Difluoro(phenyl)methanesulfonyl fluoride
  • 6-Fluoro-1H-pyrrolo[2,3-B]pyridin-3-amine hcl
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 3-((4-methyl-4H-1,2,4-triazol-3-yl)sulfonyl)-N-(thiophen-2-ylmethyl)azetidine-1-carboxamide