3-Quinolinamine

Names

[ CAS No. ]:
580-17-6

[ Name ]:
3-Quinolinamine

[Synonym ]:
EINECS 209-455-1
MFCD00006772
3-Aminoquinoline
3-Quinolinamine
quinolin-3-amine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
311.4±15.0 °C at 760 mmHg

[ Melting Point ]:
91-92 °C(lit.)

[ Molecular Formula ]:
C₉H₈N₂

[ Molecular Weight ]:
144.173

[ Flash Point ]:
167.8±7.6 °C

[ Exact Mass ]:
144.068741

[ PSA ]:
38.91000

[ LogP ]:
1.49

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.708

[ Water Solubility ]:
slightly soluble in hot water

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA9622000

CHEMICAL NAME :: Quinoline, 3-amino-

CAS REGISTRY NUMBER :: 580-17-6

BEILSTEIN REFERENCE NO. :: 0113317

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H8-N2

MOLECULAR WEIGHT :: 144.19

WISWESSER LINE NOTATION :: T66 BNJ DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 5 umol/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 187,191,1987

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38;R68

[ Safety Phrases ]:
S26-S36-S36/37/39-S22

[ RIDADR ]:
2811.0

[ WGK Germany ]:
3

[ RTECS ]:
VA9622000

[ HS Code ]:
29334990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3-Bromoquinoline
N-allyl-3-quinolylamine
3-Iodoquinoline
3-azidoquinoline
3-Nitro-quinoline 1-oxide
Quinoline, 3-nitro-
2,4-DICHLORO-3-NITRO-QUINOLINE
Formylaniline
Ethanethiol

DownStream

3-isothiocyanatoquinoline
3-amino-1H-quinoline-4-thione
3-Chloroquinoline
Quinoline, 3-fluoro-
2-methyl-4H-[1,4]thiazino[3,2-c]quinolin-3-one
2-Aminothiazolo[4,5-c]quinoline
Quinoline-3-boronic acid pinacol ester
1,2,3,4-Tetrahydro-3-quinolinamine
benzo[f][1,7]naphthyridine
3-(Trifluoromethyl)quinoline

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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