3-Quinolinamine

3-Quinolinamine Structure
3-Quinolinamine structure
Common Name 3-Quinolinamine
CAS Number 580-17-6 Molecular Weight 144.173
Density 1.2±0.1 g/cm3 Boiling Point 311.4±15.0 °C at 760 mmHg
Molecular Formula C9H8N2 Melting Point 91-92 °C(lit.)
MSDS Chinese USA Flash Point 167.8±7.6 °C
Symbol GHS07
GHS07
Signal Word Warning

Fucosylated surfactant protein-D is a biomarker candidate for the development of chronic obstructive pulmonary disease.

J. Proteomics 127 , 386-94, (2015)

We previously reported that knockout mice for α1,6-fucosyltransferase (Fut8), which catalyzes the biosynthesis of core-fucose in N-glycans, develop emphysema and that Fut8 heterozygous knockout mice are more sensitive to cigarette smoke-induced emphysema than...

Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS.

Analyst 140(2) , 467-75, (2014)

Tandem mass spectrometry (MS/MS)-based relative quantification by isobaric labeling is a useful technique to compare different metabolic expression levels in biological systems. For the first time, we have labeled primary and secondary amine-containing small ...

Distribution study of atorvastatin and its metabolites in rat tissues using combined information from UHPLC/MS and MALDI-Orbitrap-MS imaging.

Anal. Bioanal. Chem 406(19) , 4601-10, (2014)

The combination of ultrahigh-resolution mass spectrometry imaging (UHRMSI) and ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC/MS/MS) was used for the identification and the spatial localization of atorvastatin (AT) an...

CuFe2O4 magnetic nanocrystal clusters as a matrix for the analysis of small molecules by negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Analyst 140 , 5287-94, (2015)

CuFe2O4 magnetic nanocrystal clusters (CuFe2O4 MNCs) were proposed as a new matrix for small molecule analysis by negative ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for the first time. We demonstrated its ...

Rapid quantitative profiling of N-glycan by the glycan-labeling method using 3-aminoquinoline/α-cyano-4-hydroxycinnamic acid.

Anal. Chem. 84(16) , 7146-51, (2012)

Protein glycosylation is a crucial phenomenon for understanding protein functions, since its patterns and degree are associated with many biological processes, such as intercellular signaling and immune response. We previously reported a novel glycan-labeling...

Electrospray mass spectrometry and fragmentation of N-linked carbohydrates derivatized at the reducing terminus.

J. Am. Soc. Mass Spectrom. 11 , 900-15, (2000)

Derivatives were prepared from N-linked glycans by reductive amination from 2-aminobenzamide, 2-aminopyridine, 3-aminoquinoline, 2-aminoacridone, 4-amino-N-(2-diethylaminoethyl)benzamide, and the methyl, ethyl, and butyl esters of 4-aminobenzoic acid. Their e...

Analysis of native milk oligosaccharides directly from thin-layer chromatography plates by matrix-assisted laser desorption/ionization orthogonal-time-of-flight mass spectrometry with a glycerol matrix.

J. Am. Soc. Mass Spectrom. 17 , 139-50, (2006)

We have recently presented a new method for direct coupling of high-performance thin-layer chromatography (HPTLC) with matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS), illustrated by the analysis of a complex ganglioside mixture. In t...

Oligosaccharides from human milk as revealed by matrix-assisted laser desorption/ionization mass spectrometry.

Anal. Biochem. 223 , 218-226, (1994)

In this study neutral and acidic oligosaccharide fractions prepared from human milk have been investigated using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). The fraction of neutral oligosaccharides was separated by gel permeation...

3-Aminoquinoline acting as matrix and derivatizing agent for MALDI MS analysis of oligosaccharides.

Anal. Chem. 82(9) , 3719-26, (2010)

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a widely used method in oligosaccharide analysis. Underivatized oligosaccharides are not well-suited for that purpose due to their low ionization efficiency; howeve...

3-Aminoquinoline/p-coumaric acid as a MALDI matrix for glycopeptides, carbohydrates, and phosphopeptides.

Anal. Chem. 86(4) , 1937-42, (2014)

Glycosylation and phosphorylation are important post-translational modifications in biological processes and biomarker research. The difficulty in analyzing these modifications is mainly their low abundance and dissociation of labile regions such as sialic ac...