SU4312

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Names

[ CAS No. ]:
5812-07-7

[ Name ]:
SU4312

[Synonym ]:
3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one
NSC 86429

Chemical & Physical Properties

[ Density]:
1.219g/cm3

[ Boiling Point ]:
497.1ºC at 760 mmHg

[ Molecular Formula ]:
C17H16N2O

[ Molecular Weight ]:
264.32200

[ Flash Point ]:
254.5ºC

[ Exact Mass ]:
264.12600

[ PSA ]:
32.34000

[ LogP ]:
3.38330

[ Index of Refraction ]:
1.683

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Articles

The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.

Br. J. Pharmacol. 168(5) , 1201-14, (2013)

SU4312, a potent and selective inhibitor of VEGF receptor-2 (VEGFR-2), has been designed to treat cancer. Recent studies have suggested that SU4312 can also be useful in treating neurodegenerative dis...

Automated image-based phenotypic analysis in zebrafish embryos.

Dev. Dyn. 238(3) , 656-63, (2009)

Presently, the zebrafish is the only vertebrate model compatible with contemporary paradigms of drug discovery. Zebrafish embryos are amenable to automation necessary for high-throughput chemical scre...


More Articles

Related Compounds

  • (Z)-SU4312 (Z)-SU4312 (Z)-SU4312
  • N-(3-aminophenyl)-N-(tert-butyl)amine
  • 2-((5-(4-bromophenyl)-1-(p-tolyl)-1H-imidazol-2-yl)thio)-N-(3-chlorophenyl)acetamide
  • N-[(2,4-Dimethylphenyl)methyl]-1-[(tetrahydro-2-furanyl)methyl]-1H-pyrazol-4-amine
  • 2-((1-benzyl-5-(3-nitrophenyl)-1H-imidazol-2-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
  • 1-([1,1'-Biphenyl]-4-yloxy)-3-(2,6-dimethylpiperidin-1-yl)propan-2-ol hydrochloride
  • 2-((1-benzyl-5-(3-nitrophenyl)-1H-imidazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide
  • 1-(2-(4-Ethylphenoxy)ethoxy)-3-(4-(2-fluorophenyl)piperazin-1-yl)propan-2-ol dihydrochloride
  • 1-benzyl-2-((4-fluorobenzyl)thio)-5-(3-nitrophenyl)-1H-imidazole
  • 2-((1-benzyl-5-(3,4-dichlorophenyl)-1H-imidazol-2-yl)thio)-1-(pyrrolidin-1-yl)ethanone
  • 2-((1-benzyl-5-(3,4-dichlorophenyl)-1H-imidazol-2-yl)thio)-1-(piperidin-1-yl)ethanone
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