SU4312

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Names

[ CAS No. ]:
5812-07-7

[ Name ]:
SU4312

[Synonym ]:
3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one
NSC 86429

Chemical & Physical Properties

[ Density]:
1.219g/cm3

[ Boiling Point ]:
497.1ºC at 760 mmHg

[ Molecular Formula ]:
C17H16N2O

[ Molecular Weight ]:
264.32200

[ Flash Point ]:
254.5ºC

[ Exact Mass ]:
264.12600

[ PSA ]:
32.34000

[ LogP ]:
3.38330

[ Index of Refraction ]:
1.683

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Articles

The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.

Br. J. Pharmacol. 168(5) , 1201-14, (2013)

SU4312, a potent and selective inhibitor of VEGF receptor-2 (VEGFR-2), has been designed to treat cancer. Recent studies have suggested that SU4312 can also be useful in treating neurodegenerative dis...

Automated image-based phenotypic analysis in zebrafish embryos.

Dev. Dyn. 238(3) , 656-63, (2009)

Presently, the zebrafish is the only vertebrate model compatible with contemporary paradigms of drug discovery. Zebrafish embryos are amenable to automation necessary for high-throughput chemical scre...


More Articles

Related Compounds

  • (Z)-SU4312 (Z)-SU4312 (Z)-SU4312
  • 2,4-Dichloro-5-methylnicotinaldehyde
  • N-{4H,5H,6H,7H,8H-cyclohepta[d][1,3]thiazol-2-yl}prop-2-enamide
  • 5-(azetidin-3-yl)-1-ethyl-1H-pyrazole
  • N-[(6-Methoxypyridin-2-yl)methyl]prop-2-enamide
  • tert-Butyl ((3R,4S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-yl)carbamate
  • N-(2,3,4,5-tetrahydro-1-benzoxepin-5-yl)prop-2-enamide
  • 6-Amino-2-chloropyridine-3-thiol
  • 2-(4-Prop-2-enoylpiperazin-1-yl)pyridine-3-carboxamide
  • Tert-butyl 2-amino-4-methylthiophene-3-carboxylate
  • 2,2-Dicyclobutylacetaldehyde
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