SU4312
SU4312 structure
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Common Name | SU4312 | ||
|---|---|---|---|---|
| CAS Number | 5812-07-7 | Molecular Weight | 264.32200 | |
| Density | 1.219g/cm3 | Boiling Point | 497.1ºC at 760 mmHg | |
| Molecular Formula | C17H16N2O | Melting Point | N/A | |
| MSDS | USA | Flash Point | 254.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.
Br. J. Pharmacol. 168(5) , 1201-14, (2013) SU4312, a potent and selective inhibitor of VEGF receptor-2 (VEGFR-2), has been designed to treat cancer. Recent studies have suggested that SU4312 can also be useful in treating neurodegenerative disorders. In this study, we assessed neuroprotection by SU431... |
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Automated image-based phenotypic analysis in zebrafish embryos.
Dev. Dyn. 238(3) , 656-63, (2009) Presently, the zebrafish is the only vertebrate model compatible with contemporary paradigms of drug discovery. Zebrafish embryos are amenable to automation necessary for high-throughput chemical screens, and optical transparency makes them potentially suited... |
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