Proparacaine Hydrochloride
Suppliers
Names
[ CAS No. ]:
5875-06-9
[ Name ]:
Proparacaine Hydrochloride
[Synonym ]:
EINECS 227-541-7
3-amino-4-propoxybenzoate de 2-(diéthylamino)éthyle chlorhydrate
2-(Diethylamino)ethyl-3-amino-4-propoxybenzolcarboxylathydrochlorid
Proxymetacaine Hydrochloride
Proxymetacaine Hcl
2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride (1:1)
Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
2-(diethylamino)ethyl 3-amino-4-propoxybenzoate,hydrochloride
PROPARACAINE HCL
Proparacaine hydrochloride
MFCD00083467
2-(diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride
ak-taine
Chemical & Physical Properties
[ Boiling Point ]:
434.4ºC at 760mmHg
[ Molecular Formula ]:
C16H27ClN2O3
[ Molecular Weight ]:
330.850
[ Flash Point ]:
216.5ºC
[ Exact Mass ]:
330.171021
[ PSA ]:
64.79000
[ LogP ]:
3.93940
[ Storage condition ]:
-20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG3065000
- CHEMICAL NAME :
- Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, hydrochloride
- CAS REGISTRY NUMBER :
- 5875-06-9
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C16-H26-N2-O3.Cl-H
- MOLECULAR WEIGHT :
- 330.90
- WISWESSER LINE NOTATION :
- 3OR BZ DVO2N2&2 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 64 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 40,133,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3371 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,269,1958 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3223 No. of Facilities: 412 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 3442 (estimated) No. of Female Employees: 2127 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H317-H319-H332
[ Precautionary Statements ]:
P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R20/21/22;R36;R43
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DG3065000
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