Proparacaine Hydrochloride
Proparacaine Hydrochloride structure
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Common Name | Proparacaine Hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 5875-06-9 | Molecular Weight | 330.850 | |
| Density | N/A | Boiling Point | 434.4ºC at 760mmHg | |
| Molecular Formula | C16H27ClN2O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 216.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Enhanced Retinal Ganglion Cell Survival in Glaucoma by Hypoxic Postconditioning After Disease Onset.
Neurotherapeutics 12(2) , 502-14, (2015) The neuroprotective efficacy of adaptive epigenetics, wherein beneficial gene expression changes are induced by nonharmful "conditioning" stimuli, is now well established in several acute, preclinical central nervous system injury models. Recently, in a mouse... |
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Differential bacterial gene expression during experimental pneumococcal endophthalmitis.
Ophthalmic Res. 53(3) , 149-61, (2015) Streptococcus pneumoniae (pneumococcus) is a potential cause of bacterial endophthalmitis in humans that can result in ocular morbidity. We sought to identify pneumococcal genes that are differentially expressed during growth in the vitreous humor of the eye ... |
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Intraocular pharmacokinetics of intravitreal vascular endothelial growth factor-Trap in a rabbit model.
Eye (Lond.) 29(4) , 561-8, (2015) To determine intraocular pharmacokinetic properties of intravitreally injected vascular endothelial growth factor (VEGF)-Trap in a rabbit model.VEGF-Trap was intravitreally injected in 18 rabbit eyes. Eyes were enucleated 1 h and 1, 2, 5, 14, and 30 days afte... |
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Role of C/EBP homologous protein in retinal ganglion cell death after ischemia/reperfusion injury.
Invest. Ophthalmol. Vis. Sci. 56(1) , 221-31, (2015) To investigate the role of C/EBP homologous protein (CHOP), a proapoptotic protein, and the unfolded protein response (UPR) marker that is involved in endoplasmic reticulum (ER) stress-mediated apoptosis in mouse retinal ganglion cell (RGC) death following is... |
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Oral immunization of mice with gamma-irradiated Brucella neotomae induces protection against intraperitoneal and intranasal challenge with virulent B. abortus 2308.
PLoS ONE 9(9) , e107180, (2014) Brucella spp. are Gram-negative, facultative intracellular coccobacilli that cause one of the most frequently encountered zoonosis worldwide. Humans naturally acquire infection through consumption of contaminated dairy and meat products and through direct exp... |
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Resolvin E1 analog RX-10045 0.1% reduces corneal stromal haze in rabbits when applied topically after PRK.
Mol. Vis. 20 , 1710-6, (2015) To perform a masked study to determine whether resolvin E1 (RvE1), a lipid-derived immunomodulator, could regulate the development of corneal haze and opacity-related myofibroblasts after opacity-generating high correction photorefractive keratectomy (PRK) in... |
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Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush.
J. Neuroinflammation 11 , 194, (2015) Glaucoma is an optic neuropathy that is characterized by the loss of retinal ganglion cells (RGCs) initiated by damage to axons in the optic nerve. The degeneration and death of RGCs has been thought to occur in two waves. The first is axogenic, caused by dir... |
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Pharmacokinetics and efficacy of Bioerodible Dexamethasone implant in Concanavalin A-induced uveitic cataract rabbit model.
Pharm. Res. 31(11) , 3179-90, (2014) To advance therapy for the treatment of concurrent uveitis and post-cataract surgical inflammation; we evaluated pharmacokinetics and pharmacodynamics of Bioerodible Dexamethasone Implant (BDI) containing 0.3 mg of dexamethasone (DXM) in Concanavalin A (Con A... |
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Thrombomodulin promotes corneal epithelial wound healing.
PLoS ONE 10(3) , e0122491, (2015) To determine the role of thrombomodulin (TM) in corneal epithelial wound healing, and to investigate whether recombinant TM epidermal growth factor-like domain plus serine/threonine-rich domain (rTMD23) has therapeutic potential in corneal epithelial wound he... |
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Comparison of the release profile and pharmacokinetics of intact and fragmented dexamethasone intravitreal implants in rabbit eyes.
J. Ocul. Pharmacol. Ther. 30(10) , 854-8, (2014) Dexamethasone intravitreal implant (DEX implant, Ozurdex(®); Allergan, Inc.) is used to treat noninfectious posterior uveitis and macular edema associated with retinal vein occlusion and diabetic retinopathy. Two recently published reports of DEX implant frag... |