L-Homocystine

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Names

[ CAS No. ]:
626-72-2

[ Name ]:
L-Homocystine

[Synonym ]:
L-Homocystine
Dl-Homocycine
(2S,2'S)-4,4'-Dithiobis(2-aminobutanoic acid)
dl-homocystine crystalline
HOMOCYSTINE,DL
Butanoic acid, 4,4'-dithiobis[2-amino-, (2S,2'S)-
QVYZ2SS2YZVQ &&L-L Form
(2S,2'S)-4,4'-Disulfanediylbis(2-aminobutanoic acid)
EINECS 210-962-5
H-DL-Hcys-OH)2
homocystine
(2S,2'S)-4,4'-Dithiobis(2-aminobutyric acid)
MFCD00020391
DL-Homocystine
H-HoCys-OH
(H-HoCys-OH)2

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
507.6±50.0 °C at 760 mmHg

[ Melting Point ]:
281-284ºC (dec.)

[ Molecular Formula ]:
C8H16N2O4S2

[ Molecular Weight ]:
268.354

[ Flash Point ]:
260.8±30.1 °C

[ Exact Mass ]:
268.055145

[ PSA ]:
177.24000

[ LogP ]:
1.03

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.619

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • DL-Homocysteine
  • 2-amino-4-benzylsulfanyl-butanoic acid
  • N5-((R)-3-(((S)-3-amino-3-carboxypropyl)disulfanyl)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine
  • L-Homocysteine, nitrite (ester) (9CI)

DownStream

  • L-2-AMINO-4-SULFOBUTYRIC ACID
  • L-Methionine
  • SAH
  • DL-Homocysteine
  • N5-((R)-3-(((S)-3-amino-3-carboxypropyl)disulfanyl)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine
  • Ethionine
  • L-Buthionine
  • L(+)-2-Aminobutyric acid
  • L-Methionine-13C,d3
  • Trifluoromethionine

Articles

Development of High-purity Certified Reference Materials for 17 Proteinogenic Amino Acids by Traceable Titration Methods.

Anal. Sci. 31 , 805-14, (2015)

To ensure the reliability of amino acid analyses, the National Metrology Institute of Japan of the National Institute of Advanced Industrial Science and Technology (NMIJ/AIST) has developed high-purit...

Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter.

Int. J. Mol. Sci. 16 , 12560-77, (2015)

Hyperhomocysteinemia (HHcy) is an independent risk factor of atherosclerosis and other cardiovascular diseases. Unfortunately, Hcy-lowering strategies were found to have limited effects in reducing ca...

The species- and site-specific acid–base properties of biological thiols and their homodisulfides

J. Pharm. Biomed. Anal. 95 , 184-92, (2014)

Cysteamine, cysteine, homocysteine, their homodisulfides and 9 related compounds were studied by ¹H NMR-pH titrations and case-tailored evaluation methods. The resulting acid-base properties are quant...


More Articles

Related Compounds

  • L-Homocystine
  • Z-L-homocystine
  • D,L-homocystine
  • L-Homocystine-d8
  • Boc-L-homocystine
  • Fmoc-L-homocystine
  • N-[(2-methoxyphenyl)methyl]-6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-amine
  • 1-{2-tert-butyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-yl}-4-{5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}piperazine
  • 2-[1-(2,3-Dimethoxybenzoyl)piperidin-4-yl]-1,8-naphthyridine
  • 9-cyclopropyl-N-(3-phenylpropyl)-9H-purin-6-amine
  • N-[(4-bromophenyl)methyl]-6-(2-methyl-1H-imidazol-1-yl)pyrimidin-4-amine
  • N-(4-fluorophenyl)-6-(1H-1,2,4-triazol-1-yl)pyrimidin-4-amine
  • 2-{1-[(1-ethyl-2-methyl-1H-imidazol-4-yl)sulfonyl]piperidin-4-yl}-1,8-naphthyridine
  • 2-[4-(6-Ethyl-5-fluoropyrimidin-4-yl)-1,4-diazepan-1-yl]-5-methoxy-1,3-benzothiazole
  • 2-[1-(2,4-Dimethoxybenzoyl)piperidin-4-yl]-1,8-naphthyridine
  • 2-{4-[(5-Cyclopropyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1,3-benzothiazole
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