L-Homocystine

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Names

[ CAS No. ]:
626-72-2

[ Name ]:
L-Homocystine

[Synonym ]:
L-Homocystine
Dl-Homocycine
(2S,2'S)-4,4'-Dithiobis(2-aminobutanoic acid)
dl-homocystine crystalline
HOMOCYSTINE,DL
Butanoic acid, 4,4'-dithiobis[2-amino-, (2S,2'S)-
QVYZ2SS2YZVQ &&L-L Form
(2S,2'S)-4,4'-Disulfanediylbis(2-aminobutanoic acid)
EINECS 210-962-5
H-DL-Hcys-OH)2
homocystine
(2S,2'S)-4,4'-Dithiobis(2-aminobutyric acid)
MFCD00020391
DL-Homocystine
H-HoCys-OH
(H-HoCys-OH)2

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
507.6±50.0 °C at 760 mmHg

[ Melting Point ]:
281-284ºC (dec.)

[ Molecular Formula ]:
C₈H₁₆N₂O₄S₂

[ Molecular Weight ]:
268.354

[ Flash Point ]:
260.8±30.1 °C

[ Exact Mass ]:
268.055145

[ PSA ]:
177.24000

[ LogP ]:
1.03

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.619

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DL-Homocysteine
2-amino-4-benzylsulfanyl-butanoic acid
N5-((R)-3-(((S)-3-amino-3-carboxypropyl)disulfanyl)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine
L-Homocysteine, nitrite (ester) (9CI)

DownStream

L-2-AMINO-4-SULFOBUTYRIC ACID
L-Methionine
SAH
DL-Homocysteine
N5-((R)-3-(((S)-3-amino-3-carboxypropyl)disulfanyl)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine
Ethionine
L-Buthionine
L(+)-2-Aminobutyric acid
L-Methionine-13C,d3
Trifluoromethionine

Articles

Development of High-purity Certified Reference Materials for 17 Proteinogenic Amino Acids by Traceable Titration Methods.

Anal. Sci. 31 , 805-14, (2015)

To ensure the reliability of amino acid analyses, the National Metrology Institute of Japan of the National Institute of Advanced Industrial Science and Technology (NMIJ/AIST) has developed high-purit...

Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter.

Int. J. Mol. Sci. 16 , 12560-77, (2015)

Hyperhomocysteinemia (HHcy) is an independent risk factor of atherosclerosis and other cardiovascular diseases. Unfortunately, Hcy-lowering strategies were found to have limited effects in reducing ca...

The species- and site-specific acid–base properties of biological thiols and their homodisulfides

J. Pharm. Biomed. Anal. 95 , 184-92, (2014)

Cysteamine, cysteine, homocysteine, their homodisulfides and 9 related compounds were studied by ¹H NMR-pH titrations and case-tailored evaluation methods. The resulting acid-base properties are quant...

L-Homocystine
Z-L-homocystine
D,L-homocystine
L-Homocystine-d8
Boc-L-homocystine
Fmoc-L-homocystine
tert-butyl 4-(morpholin-2-yl)-1H-imidazole-1-carboxylate
tert-butyl N-[1-amino-3-(4-cyclopropyl-1,3-thiazol-5-yl)propan-2-yl]carbamate
3-(2-Methoxy-4-nitrophenyl)propan-1-amine
tert-butyl N-{2-[1-(aminooxy)ethyl]-4-chlorophenyl}carbamate
tert-butyl N-[2-amino-2-(2,6-difluoro-3-methylphenyl)ethyl]carbamate
[1-(1-phenyl-1H-1,2,3-triazol-4-yl)cyclopropyl]methanamine
tert-butyl N-[(2S)-2-aminopropyl]-N-(propan-2-yl)carbamate
tert-butyl N-[3-(2-amino-1-hydroxyethyl)-4-fluorophenyl]carbamate
Tert-butyl 4-(5-aminopent-3-en-1-yl)piperazine-1-carboxylate
Tert-butyl 4-[amino(4-fluorophenyl)methyl]-4-hydroxypiperidine-1-carboxylate

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