L-Homocystine
L-Homocystine structure
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Common Name | L-Homocystine | ||
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| CAS Number | 626-72-2 | Molecular Weight | 268.354 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 507.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C8H16N2O4S2 | Melting Point | 281-284ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 260.8±30.1 °C | |
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Development of High-purity Certified Reference Materials for 17 Proteinogenic Amino Acids by Traceable Titration Methods.
Anal. Sci. 31 , 805-14, (2015) To ensure the reliability of amino acid analyses, the National Metrology Institute of Japan of the National Institute of Advanced Industrial Science and Technology (NMIJ/AIST) has developed high-purity certified reference materials (CRMs) for 17 proteinogenic... |
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Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter.
Int. J. Mol. Sci. 16 , 12560-77, (2015) Hyperhomocysteinemia (HHcy) is an independent risk factor of atherosclerosis and other cardiovascular diseases. Unfortunately, Hcy-lowering strategies were found to have limited effects in reducing cardiovascular events. The underlying mechanisms remain uncle... |
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The species- and site-specific acid–base properties of biological thiols and their homodisulfides
J. Pharm. Biomed. Anal. 95 , 184-92, (2014) Cysteamine, cysteine, homocysteine, their homodisulfides and 9 related compounds were studied by ¹H NMR-pH titrations and case-tailored evaluation methods. The resulting acid-base properties are quantified in terms of 33 macroscopic and 62 microscopic protona... |
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Genetics of hyperhomocysteinaemia in cardiovascular disease.
Ann. Clin. Biochem. 40 , 46-59, (2003) Homocysteine, a sulphur amino acid, is a branch-point intermediate of methionine metabolism. It can be degraded in the transsulphuration pathway to cystathionine, or remethylated to methionine via the remethylation pathway. In both pathways, major genetic def... |
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Direct detection of biologically significant thiols and disulfides with manganese(IV) chemiluminescence.
Anal. Chem. 83 , 6034-6039, (2011) The quantification of low-molecular mass thiols and disulfides involved in cellular redox processes is hindered by oxidation or degradation of analytes during conventional sample preparation steps (including deproteinization and derivatization). Researchers t... |
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Mechanisms of homocysteine toxicity in humans.
Amino Acids 32 , 561-572, (2007) Homocysteine, a non-protein amino acid, is an important risk factor for ischemic heart disease and stroke in humans. This review provides an overview of homocysteine influence on endothelium function as well as on protein metabolism with a special respect to ... |
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Experimental evidence of oxidative stress in plasma of homocystinuric patients: a possible role for homocysteine.
Mol. Genet. Metab. 104 , 112-117, (2011) Homocystinuria is an inherited disorder biochemically characterized by high urinary excretion of homocystine and increased levels of homocysteine (Hcy) and methionine in biological fluids. Affected patients usually have a variety of clinical and pathologic ma... |
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Biochemistry of homocysteine in health and diseases.
Indian J. Biochem. Biophys. 43 , 275-283, (2006) The amino acid homocysteine (Hcy), formed from methionine has profound importance in health and diseases. In normal circumstances, it is converted to cysteine and partly remethylated to methionine with the help of vit B12 and folate. However, when normal meta... |