Gamma-glutamylcysteine

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Names

[ CAS No. ]:
636-58-8

[ Name ]:
Gamma-glutamylcysteine

[Synonym ]:
Glutathione Impurity D
L-gamma-glutamyl-L-cysteine
(2S)-2-amino-5-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-5-oxopentanoic acid
g-L-Glutamyl-L-cysteine
5-L-Glutamyl-L-cysteine
(S)-2-amino-5-(((R)-1-carboxy-2-mercaptoethyl)amino)-5-oxopentanoic acid
(Des-Gly)-Glutathione (reduced)

Chemical & Physical Properties

[ Density]:
1.436g/cm3

[ Boiling Point ]:
592.4ºC at 760 mmHg

[ Melting Point ]:
167℃

[ Molecular Formula ]:
C8H14N2O5S

[ Molecular Weight ]:
250.27200

[ Flash Point ]:
312.1ºC

[ Exact Mass ]:
250.06200

[ PSA ]:
168.52000

[ Index of Refraction ]:
1.57

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • phthaloyl-l-glutamic anhydride
  • (R)-3-L-γ-glutamyl-2,2-dimethyl-thiazolidine-4-carboxylic acid
  • L-cysteine
  • L-(+)Sodium glutamate
  • bis-gamma-glutamylcystine
  • L-alanine
  • Glutathione
  • L(-)-Glutathione
  • N-benzyloxycarbonyl-L-glutamic acid-5-hydrazide

DownStream

  • L-cysteine
  • Glutathione

Articles

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

Free fatty acids enhance the oxidative damage induced by ethanol metabolism in an in vitro model.

Food Chem. Toxicol. 76 , 109-15, (2015)

In recent years, there has been a growing interest to explore the responsiveness to injury in steatotic hepatocyte. VL-17A cells, which express ADH and Cyp2E1 overloaded with free fatty acids (1 mM of...

Endogenic oxidative stress response contributes to glutathione over-accumulation in mutant Saccharomyces cerevisiae Y518.

Appl. Microbiol. Biotechnol. 99 , 7069-78, (2015)

Mechanisms of glutathione (GSH) over-accumulation in mutant Saccharomyces cerevisiae Y518 screened by ultraviolet and nitrosoguanidine-induced random mutagenesis were studied. Y518 accumulated higher ...


More Articles

Related Compounds

  • gamma-glutamylcysteine
  • Gamma-glutamylcysteine TFA
  • gamma-glutaminyl-4-hydroxy-3-iodobenzene
  • gamma-ionone
  • Gamma Acid
  • gamma-tetrazole-aminopterin
  • (2R)-1-(2,2,2-trifluoroethoxy)propan-2-amine
  • [(2S)-2-amino-3,3-dimethylbutyl]dimethylamine
  • N-[2-(1-cyclohexen-1-yl)ethyl]-1-isopropyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
  • Methyl 5-cyano-1-[2-(dimethylamino)-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarboxylate
  • N-(2-(cyclohex-1-en-1-yl)ethyl)-1-(tetrazolo[1,5-b]pyridazin-6-yl)piperidine-4-carboxamide
  • (4-Carbamoylphenyl) 2-chloropyridine-3-carboxylate
  • 3-(1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)-N-(3,4,5-trimethoxyphenyl)propanamide
  • 1,3-Diethyl 2-(pyridin-3-ylformamido)propanedioate
  • Diethyl({[4-(methyloxy)phenyl]carbonyl}amino)propanedioate
  • Diethyl 2-(3-methylbenzamido)malonate
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