Thapsigargin

Suppliers

Names

[ Name ]:
Thapsigargin

[Synonym ]:
Pamoic acid disodium salt
Octanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6-dimethyl-8-[[(3Z)-3-methyl-1-oxo-3-penten-1-yl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl ester
(3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-Acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6-dimethyl-8-{[(3Z)-3-methyl-3-pentenoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate
sesquiterpene lactone tetraester
Thallium mononitrate
thallous nitrate TlNO3,orthorhombic
Thapsigargin
MFCD00083511
THALLIUM NITRATE
THALLOUS NITRATE
rcrawastenumberu217
thallous
sesquiterpene lactone
Thapsigargin,(3S,3aR,4S,6S,6AR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yloctanoate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
699.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₄H₅₀O₁₂

[ Molecular Weight ]:
650.754

[ Flash Point ]:
209.0±25.0 °C

[ Exact Mass ]:
650.330200

[ PSA ]:
171.96000

[ LogP ]:
6.61

[ Appearance of Characters ]:
liquid or film

[ Vapour Pressure ]:
0.0±5.0 mmHg at 25°C

[ Index of Refraction ]:
1.540

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMSO: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H334-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn,T

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin . R42:May cause sensitization by inhalation.

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
3

Articles

Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells.

Biochim. Biophys. Acta 1853(2) , 377-87, (2015)

Macroautophagy (autophagy) is an important factor affecting the function of vascular endothelial cells (VECs) and must be tightly regulated in these cells. However, the precise mechanisms underlying t...

Identification of the cellular mechanisms that modulate trafficking of frizzled family receptor 4 (FZD4) missense mutants associated with familial exudative vitreoretinopathy.

Invest. Ophthalmol. Vis. Sci. 55(6) , 3423-31, (2014)

Fifteen missense mutations in the frizzled family receptor 4 (FZD4) reported to cause familial exudative vitreoretinopathy (FEVR) were evaluated to establish the pathological cellular mechanism of dis...

Improved plasma membrane expression of the trafficking defective P344R mutant of muscle, skeletal, receptor tyrosine kinase (MuSK) causing congenital myasthenic syndrome.

Int. J. Biochem. Cell Biol. 60 , 119-29, (2015)

Muscle, skeletal, receptor tyrosine kinase (MuSK) is a key organizer at the postsynaptic membrane and critical for proper development and maintenance of the neuromuscular junction. Mutations in MUSK r...

Thapsigargin
BODIPY FL Thapsigargin
O8-Debutanoylthapsigargin
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
4-(Cyclohexyloxy)-2-(trifluoromethyl)phenol
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
N-(benzo[d]thiazol-2-yl)-2-(6-fluoro-2-methyl-4-oxoquinazolin-3(4H)-yl)acetamide
tert-Butyl-DL-alanine