(S)-Mephenytoin

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Names

[ CAS No. ]:
70989-04-7

[ Name ]:
(S)-Mephenytoin

[Synonym ]:
S(+)-5-Ethyl-3-methyl-5-phenylhydantoin
S(+)-5-Ethyl-1-methyl-5-phenylbarbituric acid
S-mephenytoin
(+)-Mephobarbitol
5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
5-éthyl-3-méthyl-5-phénylimidazolidine-2,4-dione
5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
(S)-Mephenytoin
mephenytoin
(5S)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
[14C]-(+)-Mephenytoin
UNII:R420KW629U
5-Ethyl-3-methyl-5-phenylimidazolidin-2,4-dion
2,4,6(1H,3H,5H)-Pyrimidinetrione,5-ethyl-1-methyl-5-phenyl-,(S)
(+)-Mephobarbital
Gerot-Epilan
(5R)-mephobarbital
(S)-5-Ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione
2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-
(S)-Methylphenobarbital
UNII-5NC67NU76B component ALARQZQTBTVLJV-ZDUSSCGKSA-N
2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, (5S)-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Melting Point ]:
135-138ºC

[ Molecular Formula ]:
C12H14N2O2

[ Molecular Weight ]:
218.252

[ Exact Mass ]:
218.105530

[ PSA ]:
49.41000

[ LogP ]:
1.40

[ Index of Refraction ]:
1.541

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

  • (S)-(+)-N,N-DIMETHYL-3-(1-NAPHTHALENYLOXY)-3-(2-THIENYL)PROPANAMINE

Articles

CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.

Malaria Journal 11 , 259, (2012)

The 8-aminoquinoline (8AQ) drug primaquine (PQ) is currently the only approved drug effective against the persistent liver stage of the hypnozoite forming strains Plasmodium vivax and Plasmodium ovale...

Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes.

Basic Clin Pharmacol Toxicol. 105(1) , 58-63, (2009)

The aim of this study was to evaluate in vitro the dose-dependent induction potential of six commonly used trade herbal products on CYP2C19 and CYP2E1 metabolic activities in cultured human hepatocyte...


More Articles

Related Compounds

  • (S)-MEPHENYTOIN
  • (S)-4-Hydroxy Mephenytoin
  • (S)-(-)-1,1-DIPHENYL-1,2-PROPANEDIOL
  • (S)-benzyl (1-((3-chloro-2-oxopropyl)amino)-1-oxopropan-2-yl)carbamate
  • (S)-1-(p-tolyl)ethyl 2,3,4,5,6-pentafluorobenzoate
  • (s)-(+)-6-methyl-5-hepten-2-ol
  • N-(5-bromopyridin-2-yl)-4,5-dimethoxy-2-nitrobenzamide
  • 2-chloro-N-[2-(1,3-thiazol-2-yl)propan-2-yl]propanamide
  • CID 85783933
  • 2',3'-Difluoro-5'-methoxyacetophenone
  • 3-(aminomethyl)-N-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)benzene-1-sulfonamide
  • (S)-(5-Oxomorpholin-2-YL)methyl 4-methylbenzenesulfonate
  • 3-(4-Bromo-2-methylphenyl)prop-2-enal
  • 3-(4-Bromo-3-methylphenyl)prop-2-enal
  • 1-[1-(Bromomethyl)cyclopropyl]-2-methylbenzene
  • 1-[1-(Bromomethyl)cyclopropyl]-4-methylbenzene
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