(S)-Mephenytoin

(S)-Mephenytoin Structure
(S)-Mephenytoin structure
Common Name (S)-Mephenytoin
CAS Number 70989-04-7 Molecular Weight 218.252
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C12H14N2O2 Melting Point 135-138ºC
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.

Malaria Journal 11 , 259, (2012)

The 8-aminoquinoline (8AQ) drug primaquine (PQ) is currently the only approved drug effective against the persistent liver stage of the hypnozoite forming strains Plasmodium vivax and Plasmodium ovale as well as Stage V gametocytes of Plasmodium falciparum. T...

Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes.

Basic Clin Pharmacol Toxicol. 105(1) , 58-63, (2009)

The aim of this study was to evaluate in vitro the dose-dependent induction potential of six commonly used trade herbal products on CYP2C19 and CYP2E1 metabolic activities in cultured human hepatocytes. S-mephenytoin and chlorzoxazone were used as specific CY...