Rutaecarpine

Names

[ CAS No. ]:
84-26-4

[ Name ]:
Rutaecarpine

[Synonym ]:
ruteacarpine
Rutecarpine
MFCD00210551
Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13-dihydro-
RUTECARPINE 95+
8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
550.1±60.0 °C at 760 mmHg

[ Melting Point ]:
259.5 - 260ºC

[ Molecular Formula ]:
C₁₈H₁₃N₃O

[ Molecular Weight ]:
287.315

[ Flash Point ]:
286.5±32.9 °C

[ Exact Mass ]:
287.105865

[ PSA ]:
50.68000

[ LogP ]:
2.03

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.792

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: 18 mg/mL clear yellow solution, soluble

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R25

[ Safety Phrases ]:
S45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Pharmacological effects of rutaecarpine as a cardiovascular protective agent.

Molecules 15(3) , 1873-81, (2010)

Many studies indicate that traditional Chinese herbs are beneficial in the prevention and treatment of cardiovascular diseases. Evodia rutaecarpa ('Wu-Chu-Yu') remains the most popular and multi-purpo...

Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo.

Fitoterapia 83(5) , 954-60, (2012)

Evodiamine (EVO) and rutaecapine (RUT), the major active components from Evodia rutaecarpa extract (EE), are recognized as a depended analgesic agent. This study was designed to investigate the effect...

Effects of rutaecarpine on the metabolism and urinary excretion of caffeine in rats.

Arch. Pharm. Res. 34(1) , 119-25, (2011)

Although rutaecarpine, an alkaloid originally isolated from the unripe fruit of Evodia rutaecarpa, has been reported to reduce the systemic exposure of caffeine, the mechanism of this phenomenon is un...