Acetohexamide
Suppliers
Names
[ CAS No. ]:
968-81-0
[ Name ]:
Acetohexamide
[Synonym ]:
Metaglucina
Gamadiabet
1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea
MFCD00072156
acetoxehamide
Acetohexamidum
Hypoglicil
Dimelin
Acetohexamid
N(2)-Cyclohexyl-N(1)-(4-acetylbenzenesulfonyl) Urea
EINECS 213-530-4
N'-<4-Acetyl-benzolsulfonyl>-N-cyclohexyl-harnstoff
N-(p-Acetyl-benzolsulfonyl)-N'-(cyclohexyl)-harnstoff
Dymelor
Dimelor
Acetohexamida
N-Cyclohexyl-N'-<4-acetyl-benzolsulfonyl>-harnstoff
Chemical & Physical Properties
[ Density]:
1.3g/cm3
[ Melting Point ]:
188-190° (GB 912789); mp 175-177° (Marshall)
[ Molecular Formula ]:
C15H20N2O4S
[ Molecular Weight ]:
324.39500
[ Exact Mass ]:
324.11400
[ PSA ]:
100.72000
[ LogP ]:
4.07240
[ Appearance of Characters ]:
solid | white
[ Index of Refraction ]:
1.581
[ Water Solubility ]:
DMSO: ~45 mg/mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YR7350000
- CHEMICAL NAME :
- Urea, 1-((p-acetylphenyl)sulfonyl)-3-cyclohexyl-
- CAS REGISTRY NUMBER :
- 968-81-0
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C15-H20-N2-O4-S
- MOLECULAR WEIGHT :
- 324.43
- WISWESSER LINE NOTATION :
- L6TJ AMVMSWR DV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,34,1995
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,18,1982 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 900 mg/kg
- SEX/DURATION :
- female 26-39 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - stillbirth
- REFERENCE :
- BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 2,187,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83998 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 627 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83998 No. of Facilities: 43 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1626 (estimated) No. of Female Employees: 833 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
YR7350000
[ HS Code ]:
2935009090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2935009090
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
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