Acetohexamide structure
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Common Name | Acetohexamide | ||
|---|---|---|---|---|
| CAS Number | 968-81-0 | Molecular Weight | 324.39500 | |
| Density | 1.3g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C15H20N2O4S | Melting Point | 188-190° (GB 912789); mp 175-177° (Marshall) | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of AcetohexamideAcetohexamide is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2; stimulate the pancreas to secrete insulin. |
| Name | acetohexamide |
|---|---|
| Synonym | More Synonyms |
| Description | Acetohexamide is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2; stimulate the pancreas to secrete insulin. |
|---|---|
| Related Catalog |
| Density | 1.3g/cm3 |
|---|---|
| Melting Point | 188-190° (GB 912789); mp 175-177° (Marshall) |
| Molecular Formula | C15H20N2O4S |
| Molecular Weight | 324.39500 |
| Exact Mass | 324.11400 |
| PSA | 100.72000 |
| LogP | 4.07240 |
| Appearance of Characters | solid | white |
| Index of Refraction | 1.581 |
| InChIKey | VGZSUPCWNCWDAN-UHFFFAOYSA-N |
| SMILES | CC(=O)c1ccc(S(=O)(=O)NC(=O)NC2CCCCC2)cc1 |
| Water Solubility | DMSO: ~45 mg/mL |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | YR7350000 |
| HS Code | 2935009090 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Therapeutic targeting of BRCA1-mutated breast cancers with agents that activate DNA repair.
Cancer Res. 74(21) , 6205-15, (2014) Cancers due to germline mutations in the BRCA1 gene tend to lack targets for approved chemoprevention agents. This study aimed at a targeted chemoprevention strategy for BRCA1-associated malignancies.... |
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Analysis of free drug fractions by ultrafast affinity extraction: interactions of sulfonylurea drugs with normal or glycated human serum albumin.
J. Chromatogr. A. 1371 , 82-9, (2014) Ultrafast affinity extraction and a multi-dimensional affinity system were developed for measuring free drug fractions at therapeutic levels. This approach was used to compare the free fractions and g... |
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CURRENT THERAPEUTICS. CCII. ACETOHEXAMIDE.
Practitioner 193 , 555-60, (1964)
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Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
|
|
Name: Increase the activity of the Burkholderia fixLJ 2-component system
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Burkholderia multivorans
External Id: HMS1625
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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|
Name: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
Source: NCGC
External Id: HERG01
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Name: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
Source: NCGC
Target: N/A
External Id: SMAD3201
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Name: uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
Source: Burnham Center for Chemical Genomics
Target: cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id: SBCCG-A764-CF-PAF-Primary-Assay
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| Metaglucina |
| Gamadiabet |
| 1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea |
| MFCD00072156 |
| acetoxehamide |
| Acetohexamidum |
| Hypoglicil |
| Dimelin |
| Acetohexamid |
| N(2)-Cyclohexyl-N(1)-(4-acetylbenzenesulfonyl) Urea |
| EINECS 213-530-4 |
| N'-<4-Acetyl-benzolsulfonyl>-N-cyclohexyl-harnstoff |
| N-(p-Acetyl-benzolsulfonyl)-N'-(cyclohexyl)-harnstoff |
| Dymelor |
| Dimelor |
| Acetohexamida |
| N-Cyclohexyl-N'-<4-acetyl-benzolsulfonyl>-harnstoff |