URAT1 inhibitor 7

Modify Date: 2024-01-04 18:01:46

URAT1 inhibitor 7 Structure
URAT1 inhibitor 7 structure
Common Name URAT1 inhibitor 7
CAS Number 1632002-28-8 Molecular Weight 428.82
Density N/A Boiling Point N/A
Molecular Formula C19H10ClFN4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of URAT1 inhibitor 7


URAT1 inhibitor 7 (compound 10f) is a potent URAT1 inhibitor, with an IC50 of 12 nM. URAT1 inhibitor 7 exhibits microsomal stability (HLM <13 µL/min/mg). URAT1 inhibitor 7 also inhibits CYP2C9, with an IC50 of 4.2 μM. URAT1 inhibitor 7 can be used for gout research[1].

 Names

Name URAT1 inhibitor 7

 URAT1 inhibitor 7 Biological Activity

Description URAT1 inhibitor 7 (compound 10f) is a potent URAT1 inhibitor, with an IC50 of 12 nM. URAT1 inhibitor 7 exhibits microsomal stability (HLM <13 µL/min/mg). URAT1 inhibitor 7 also inhibits CYP2C9, with an IC50 of 4.2 μM. URAT1 inhibitor 7 can be used for gout research[1].
Related Catalog
References

[1]. Storer R I, et al. The discovery and evaluation of diaryl ether heterocyclic sulfonamides as URAT1 inhibitors for the treatment of gout. MedChemComm, 2016:10.1039.C6MD00190D.

 Chemical & Physical Properties

Molecular Formula C19H10ClFN4O3S
Molecular Weight 428.82
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