Permethrin-d5

Modify Date: 2024-01-14 13:01:15

Permethrin-d5 structure	Common Name	Permethrin-d5
	CAS Number	1794760-19-2	Molecular Weight	396.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₅D₅Cl₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Permethrin-d5

Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].

Name	Permethrin-d5

Description	Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].
Related Catalog	Research Areas >> Infection
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416. [3]. Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12(11):e0006933.

Molecular Formula	C₂₁H₁₅D₅Cl₂O₃
Molecular Weight	396.32

Permethrin-d5

Use of Permethrin-d5

Names

Permethrin-d5 Biological Activity

Chemical & Physical Properties