FLT3-IN-16

Modify Date: 2024-04-07 16:35:23

FLT3-IN-16 structure	Common Name	FLT3-IN-16
	CAS Number	298207-49-5	Molecular Weight	301.36
	Density	1.391±0.06 g/cm3(Predicted)	Boiling Point	394.8±42.0 °C(Predicted)
	Molecular Formula	C₁₅H₁₅N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FLT3-IN-16

FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1].

Name	N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide

Description	FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3
Target	IC50: 1.1 μM (FLT3)[1]
In Vitro	FLT3-IN-16 (compound 9, 0-10 μM) exhibits anti-proliferative activities against MV4-11 cells with an IC50 value of 2.0 μM[1].
References	[1]. Patch RJ, et, al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6.

Density	1.391±0.06 g/cm3(Predicted)
Boiling Point	394.8±42.0 °C(Predicted)
Molecular Formula	C₁₅H₁₅N₃O₂S
Molecular Weight	301.36
Storage condition	-20°C