2-乙烯基吡啶
2-乙烯基吡啶用途
主要用于合成丁苯吡胶乳，也用于制造克矽平、倍他定盐酸盐等药物
【用途二】
该品与丁二烯、苯乙烯共聚可制成乙烯基吡啶改性的胶乳，也用于粘结剂。聚2-乙烯吡啶氧化得到防治矽肺病的药物克矽平；该品也是血管扩张药培他啶盐酸盐的中间体。还用于照相底片消晕层及高分子电解质。
2-乙烯基吡啶名称
[ CAS 号 ]:
100-69-6
[ 中文名 ]:
2-乙烯吡啶
[ 英文名 ]:
2-Vinylpyridine
[中文别名 ]:
[英文别名 ]:
- 2-Ethenylpyridin
- 2-Ethenylpyridine
- 2-Ethenylpryridine
- vinyl-pyridine
- 2-Vinylpyridine
- EINECS 202-879-8
- Pyridine,2-ethenyl
- 2VP
- T6NJ B1U1
- MFCD00006355
2-乙烯基吡啶物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
160.3±9.0 °C at 760 mmHg
[ 熔点 ]:
-50 °C
[ 分子式 ]:
C7H7N
[ 分子量 ]:
105.137
[ 闪点 ]:
46.7±0.0 °C
[ 精确质量 ]:
105.057846
[ PSA ]:
12.89000
[ LogP ]:
1.34
[ 外观性状 ]:
暗棕色液体带有一种令人不愉快的气味
[ 蒸汽压 ]:
3.1±0.3 mmHg at 25°C
[ 折射率 ]:
1.563
[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运
[ 稳定性 ]:
Unstable; may be stabilized with a small amount of ter-butyl catechol. Heat sensitive - store cold. Flammable. Incompatible with strong oxidizing agents, strong bases, strong acids.
[ 水溶解性 ]:
2.5 g/100 mL (20 ºC)
2-乙烯基吡啶MSDS
2-乙烯基吡啶毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UU1040000
- CHEMICAL NAME :
- Pyridine, 2-vinyl-
- CAS REGISTRY NUMBER :
- 100-69-6
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C7-H7-N
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,845,1986
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 610 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 57(9-10),64,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 420 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 10(3),9,1966
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 460 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 10(3),9,1966
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,845,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 415 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 mg/m3/4H/48W-I
- TOXIC EFFECTS :
- Behavioral - alteration of classical conditioning Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 10(3),9,1966
2-乙烯基吡啶安全信息
[ 符号 ]:
GHS02, GHS05, GHS06, GHS09
[ 信号词 ]:
Danger
[ 危害声明 ]:
H226-H302-H311-H314-H317-H411
[ 补充危害声明 ]:
Corrosive to the respiratory tract.
[ 警示性声明 ]:
P273-P280-P305 + P351 + P338-P310
[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
T:Toxic;
[ 风险声明 (欧洲) ]:
R10;R20;R25;R34;R42/43
[ 安全声明 (欧洲) ]:
S16-S23-S26-S36/37/39-S45-S28A
[ 危险品运输编码 ]:
UN 3073 6.1/PG 2
[ WGK德国 ]:
3
[ RTECS号 ]:
UU1040000
[ 包装等级 ]:
II
[ 危险类别 ]:
6.1
[ 海关编码 ]:
2933399090
2-乙烯基吡啶合成路线
2-乙烯基吡啶上下游产品
2-乙烯基吡啶上游产品
2-乙烯基吡啶下游产品
2-乙烯基吡啶制备
1、由2-羟乙基吡啶脱水而得。
2、由2-甲基吡啶与甲醛反应 配料比为2-甲基吡啶：甲醛：氢氯化钠溶液（50%）=1：0.4：0.1。将2-甲基吡啶和甲醛混合均匀，经柱塞泵打入管道反应器，控制流量使反应液停留时间为8min，保持压力9.08MPa，温度250℃±2℃，进行加成反应，得3-羟乙基吡啶溶液，收率30%。由所得的2-羟乙基吡啶溶液回收未反应的2-甲基吡啶，加入50%氢氧化钠溶液洗涤，精馏后套用。剩余液中加入50%氢氧化钠溶液，加热回流脱水，然后减压蒸馏，收集70℃（8.0kpa）以上馏分，得粗品2-乙烯基吡啶；当温度达160℃时停止收集，再进行精馏，收集70℃（2.67kpa）以上馏分，即得2-乙烯基吡啶精品，收率30%，气相层析测含量在98%以上。
2-乙烯基吡啶海关
[ 海关编码 ]: 2933399090
[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
2-乙烯基吡啶文献
Food Chem. Toxicol. 71 , 97-105, (2014)
The aim of this study was to explore the oxidative properties of ochratoxin A (OTA) and citrinin (CTN) as a possible underlying mechanism of their individual and/or combined cytotoxicity. Metabolic ac...
Self assembled nano fibers of betulinic acid: A selective inducer for ROS/TNF-alpha pathway mediated leukemic cell death.Bioorg. Chem. 63 , 85-100, (2015)
The main complication in betulinic acid (BA) based drug delivery has been observed due to its bulk structure. The present study demonstrates the potential effects of self assembled nano size betulinic...
Sulfur amino acid metabolism in Zucker diabetic fatty rats.Biochem. Pharmacol. 96 , 256-66, (2015)
The present study was aimed to investigate the metabolomics of sulfur amino acids in Zucker diabetic fatty (ZDF) rats, an obese type 2 diabetic animal model. Plasma levels of total cysteine, homocyste...
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公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
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产品详情：2-乙烯吡啶
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥118.0/25ml
￥348.0/100ml
联系人：刘佳
产品详情：2-乙烯吡啶
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥需询单/1mg
￥需询单/1mg
￥需询单/1mg
￥需询单/1mg
联系人：阿拉丁
产品详情：2-乙烯吡啶
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相关化合物
【2-乙烯基吡啶】化源网提供2-乙烯基吡啶CAS号100-69-6，2-乙烯基吡啶MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询2-乙烯基吡啶上化源网，专业又轻松。>>电脑版：2-乙烯基吡啶
标题：2-乙烯基吡啶_MSDS_用途_密度_CAS号【100-69-6】_化源网 地址：https://m.chemsrc.com/mip/cas/100-69-6_752643.html