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环戊胺

环戊胺用途

用于制药工业

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环戊胺名称

[ CAS 号 ]:
1003-03-8

[ 中文名 ]:
环戊胺

[ 英文名 ]:
Cyclopentylamine

[中文别名 ]:

氨基环戊烷

[英文别名 ]:

MFCD00001380
EINECS 213-697-3
Aminocyclopentane
UNII-4259VRY3GN
cyclopentanamine

环戊胺物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
110.0±8.0 °C at 760 mmHg

[ 熔点 ]:
-85°C

[ 分子式 ]:
C₅H₁₁N

[ 分子量 ]:
85.147

[ 闪点 ]:
17.2±0.0 °C

[ 精确质量 ]:
85.089149

[ PSA ]:
26.02000

[ LogP ]:
0.83

[ 外观性状 ]:
透明至黄色液体

[ 蒸汽压 ]:
24.2±0.2 mmHg at 25°C

[ 折射率 ]:
1.465

[ 储存条件 ]:
Flammables area

[ 水溶解性 ]:
MISCIBLE

环戊胺MSDS

环戊胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY8452000

CHEMICAL NAME :: Cyclopentylamine

CAS REGISTRY NUMBER :: 1003-03-8

BEILSTEIN REFERENCE NO. :: 0635706

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C5-H11-N

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

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环戊胺安全信息

[ 符号 ]:

GHS02, GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H300-H315-H317-H318-H332

[ 警示性声明 ]:
P210-P264-P280-P301 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F:Flammable;T:Toxic;

[ 风险声明 (欧洲) ]:
R11;R20;R25;R34;R43

[ 安全声明 (欧洲) ]:
S16-S45-S36/37/39-S25-S26

[ 危险品运输编码 ]:
UN 2733 3/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
GY8452000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
29213099

环戊胺合成路线

环戊胺上下游产品

环戊胺上游产品

环戊胺下游产品

环戊胺制备

由环戊烷羧酸经环戊烷甲酰胺和霍夫曼降解(Hofmann degadation)合成。

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环戊胺海关

[ 海关编码 ]: 2921300090

[ 中文概述 ]:
2921300090 其他环（烷，烯，萜烯）单胺或多胺（包括其衍生物及它们的盐）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

环戊胺文献

Structure-kinetic relationships--an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as chemokine receptor 2 antagonists.

J. Med. Chem. 56(19) , 7706-14, (2013)

Preclinical models of inflammatory diseases (e.g., neuropathic pain, rheumatoid arthritis, and multiple sclerosis) have pointed to a critical role of the chemokine receptor 2 (CCR2) and chemokine liga...

Cytostatic and antitumour properties of a new series of Pt (II) complexes with cyclopentylamine.

In Vivo 1(4) , 229-34, (1987)

Ten new Pt (II) complexes were synthesized and tested as potential antitumor drugs in vitro on KB human tumour cell line, and in vivo against four experimental tumour systems (P388, L1210, ADJ/PC6A an...

Influenza virus M2 protein: a molecular modelling study of the ion channel.

Protein Eng. 6(1) , 65-74, (1993)

The influenza A M2 protein forms cation-selective ion channels which are blocked by the anti-influenza drug amantadine. A molecular model of the M2 channel is presented in which a bundle of four paral...

更多文献

环戊胺

环戊胺用途

环戊胺名称

环戊胺物理化学性质

环戊胺MSDS

详细MSDS(安全技术说明书)

环戊胺毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

环戊胺安全信息

环戊胺合成路线

详细合成路线

环戊胺上下游产品

环戊胺上游产品

环戊胺下游产品

环戊胺制备

环戊胺海关

环戊胺文献

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