氢溴酸

氢溴酸用途

【用途一】
用于制造各种溴化合物，也可用于医药、染料、香料等工业
【用途二】
用于高纯度的提炼及溴化物的合成，也用作分析试剂
【用途三】
是制造各种无机溴化物如溴化钠、溴化钾、溴化锂和溴化钙等和某些烷基溴化物如溴甲烷、溴乙烷等的基本原料。医药上用以合成镇静剂和麻醉剂等。也是一些金属矿物的良好溶剂，用于高纯金属的提炼。石油工业用作烷氧基和苯氧基化合物的分离剂、脂环烃及链烃氧化为酮、酸或过氧化物的催化剂。也用于合成染料和香料等。
【用途四】
用于无机和有机溴化物的制造；还用于合成香料、染料等。
【用途五】
用作分析试剂。测定硫和硒，从砷和锑中分离锡，测定铋、锌和铁，烷化催化剂

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氢溴酸名称

[ CAS 号 ]:
10035-10-6

[ 中文名 ]:
氢溴酸

[ 英文名 ]:
Hydrogen bromide

[中文别名 ]:

[英文别名 ]:

acidobromhidrico
EINECS 233-113-0
acidobromidrico
Hydobromic acid
Hydrobromic
Hydrogenbromid
MFCD00011323
Hydrobromic Acid
Bromwasserstoff
Bromowodor

氢溴酸物理化学性质

[ 密度 ]:
1.49 g/mL at 25 °C(lit.)

[ 沸点 ]:
−67 °C(lit.)

[ 熔点 ]:
−87 °C(lit.)

[ 分子式 ]:
BrH

[ 分子量 ]:
80.91190

[ 闪点 ]:
40°C

[ 精确质量 ]:
79.92620

[ LogP ]:
0.95810

[ 外观性状 ]:
无色气体带有一种辛辣,令人窒息的气味

[ 蒸汽密度 ]:
2.8 (vs air)

[ 蒸汽压 ]:
654mmHg at 25°C

[ 折射率 ]:
n20/D 1.438

[ 储存条件 ]:
库房通风低温干燥,与氰化物、H发孔剂、碱类分开存放

[ 稳定性 ]:
Stable. Incompatible with strong bases, strong oxidizing agents, ammonia, ozone, fluorine, water, metals. Air and light sensitive.

[ 水溶解性 ]:
soluble

氢溴酸MSDS

详细MSDS(安全技术说明书)

氢溴酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MW3850000

CHEMICAL NAME :: Hydrobromic acid

CAS REGISTRY NUMBER :: 10035-10-6

LAST UPDATED :: 199712

DATA ITEMS CITED :: 30

MOLECULAR FORMULA :: Br-H

MOLECULAR WEIGHT :: 80.92

WISWESSER LINE NOTATION :: H E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2858 ppm/1H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB214-270

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 76 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 41(1),105,1976

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 814 ppm/1H

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB214-270 *** REVIEWS *** ACGIH TLV-CL 9.9 mg/m3 (3 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 3 ppm (10 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,128,1971 OSHA PEL (Gen Indu):8H TWA 3 ppm (10 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 3 ppm (10 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 3 ppm (10 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 3 ppm (10 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 3 ppm (10 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 5 ppm (17 mg/m3) JAN 1993 OEL-BELGIUM:STEL 3 ppm (9.9 mg/m3) JAN 1993 OEL-DENMARK:TWA 3 ppm (10 mg/m3) JAN 1993 OEL-FINLAND:STEL 3 ppm (10 mg/m3);Skin JAN 1993 OEL-GERMANY:TWA 5 ppm (17 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 3 ppm (10 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 3 ppm (10 mg/m3) JAN 1993 OEL-POLAND:TWA 7 mg/m3 JAN 1993 OEL-RUSSIA:STEL 2 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 3 ppm (10 mg/m3);STEL 6 ppm (20 mg/m3) JAN 1993 OEL-TURKEY:TWA 5 ppm (17 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 3 ppm (10 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO HYDROGEN BROMIDE-air:CL 3 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 38575 No. of Facilities: 510 (estimated) No. of Industries: 13 No. of Occupations: 12 No. of Employees: 2643 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 38575 No. of Facilities: 1103 (estimated) No. of Industries: 23 No. of Occupations: 26 No. of Employees: 20571 (estimated) No. of Female Employees: 5398 (estimated)

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氢溴酸安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314-H335

[ 警示性声明 ]:
P260-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R10;R34;R37

[ 安全声明 (欧洲) ]:
S26-S45-S7/9

[ 危险品运输编码 ]:
UN 3265 8/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
MW3850000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
2811199090

氢溴酸合成路线

详细合成路线

氢溴酸上下游产品

氢溴酸上游产品

氢溴酸下游产品

氢溴酸制备

1.赤磷法先将赤磷放入盛水的反应器中，在搅拌下缓慢加入溴素，反应生成氢溴酸和亚磷酸，通过沉降、过滤、蒸馏制得氢溴酸成品。其反应方程式如下：

2.二氧化硫法将二氧化硫通入加有溴和碎冰的反应釜中，保持温度在20℃以下进行反应直至溶液呈黄色。将混合溶液进行蒸馏，蒸出溶液加入氢氧化钡溶液与生成的硫酸反应，生成硫酸钡沉淀。经静置，过滤，除去沉淀，再蒸馏滤液即得氢溴酸成品。其反应方程式如下：

3.溴素与氢气在活性炭催化剂存在下直接合成溴化氢。然后蒸馏、提纯，制得溴化氢。其反应式如下：

4.在催化剂FeBr3存在下，将苯溴化。在烧瓶中放置200g无水苯和几克溴化铁(或铁粉)，然后，将烧瓶用涂石蜡的塞子，塞好，塞子上插有滴液漏斗和排气管，经滴液漏斗缓慢加入135mL溴(在负压下)。这时会发生激烈反应(烧瓶应用水冷却)，并均匀地放出溴化氢。出来的气体通过一U型管，它的一端装满FeBr3以吸收苯，另一端装满蒽以结合带出来的溴。溴与含水的红磷作用。在烧瓶中放10g红磷，20mL水。经滴液漏斗在负压下缓慢加入35mL溴。为了将出来的气体提纯，使它通过一个充满石棉与含水(但不是湿的)红磷混合物的U型管。被提纯的氢溴酸用氯仿萃取，分去水相进行蒸馏。62℃时蒸出少量氯仿，在125～126℃蒸出氢溴酸(相对密度1.473)。

5.在200毫升水中加入120克粉末状的溴化钾。将容器放在冷水中，并缓侵地加入90毫升浓硫酸(1.7克分子)。温度应不使超过75℃，否则就会生成少量的游离澳。不过，生成少t的嗅并不重要，因为它将在蒸馏过程中随沸点为100-115℃之间的馏份而蒸馏出来。将溶液冷却至室温，并在玻芯漏斗中滤出酸式硫酸钾。将滤液放在500毫升蒸馏瓶中，装上水冷凝器和接受器，并放在铁丝网上加热。溶液中有0.01一0.015%的硫酸根离子并无妨碍，将比恒沸混合物沸点低1℃，开始馏出的蒸镭液保留起来。当温度下降时应立即停止蒸馏。溶液的比重是会改变的，因为蒸馏液的组成会随着大气压力而发生改变，所得产率约为85%。将低沸点的馏份进行再蒸馏就可以增大产率。如果需要不含硫酸根离子的值沸液，在比恒沸液馏出温度低5℃时即开始收集蒸馏液，将这个酸进行再蒸馏，并仅收集在恒沸点时馏出的溶液以获得比重最大的恒沸酸。在第二次蒸馏之前加入氢氧化钡并不能制得更纯些的产物。产率约近似地为计算量的86%。将氢溴酸与氯化亚锡一道蒸馏，可得无色的氢溴酸。

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氢溴酸海关

[ 海关编码 ]: 2811199090

氢溴酸文献

The protein phosphatase Siw14 controls caffeine-induced nuclear localization and phosphorylation of Gln3 via the type 2A protein phosphatases Pph21 and Pph22 in Saccharomyces cerevisiae.

J. Biochem. 157(1) , 53-64, (2015)

The Saccharomyces cerevisiae Siw14, a tyrosine phosphatase involved in the response to caffeine, participates in regulation of the phosphorylation and intracellular localization of Gln3, a GATA transc...

Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.

Bioorg. Med. Chem. Lett. 21 , 710-4, (2011)

The catalytic activity and the inhibition of a new coral carbonic anhydrase (CA, EC 4.2.1.1), from the scleractinian coral Stylophora pistillata, STPCA-2, has been investigated. STPCA-2 has high catal...

Molecularly imprinted polymers with synthetic dummy template for simultaneously selective removal and enrichment of ginkgolic acids from Ginkgo biloba L. leaves extracts.

J. Chromatogr. A. 1368 , 44-51, (2014)

Dummy molecularly imprinted polymers (DMIPs) for simultaneously selective removal and enrichment of ginkgolic acids (GAs) during the processing of Ginkgo biloba leaves have been prepared. Two dummy te...

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氢溴酸

氢溴酸用途

氢溴酸名称

氢溴酸物理化学性质

氢溴酸MSDS

详细MSDS(安全技术说明书)

氢溴酸毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

氢溴酸安全信息

氢溴酸合成路线

详细合成路线

氢溴酸上下游产品

氢溴酸上游产品

氢溴酸下游产品

氢溴酸制备

氢溴酸海关

氢溴酸文献

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