(Rac)-Golgicide A

(Rac)-Golgicide A用途

(Rac)-高尔基体A((Rac)-GCA)是高尔基体A的外消旋体。高尔基体A(GCA)是顺式高尔基体ADP核糖基化因子鸟嘌呤核苷酸交换因子(ArfGEF)GBF1的有效、高度特异和可逆抑制剂[1]。Golgicide是柯萨奇病毒B3(CVB3)和其他人类肠道病毒种类的复制大幅减少[2]。

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(Rac)-Golgicide A名称

[ CAS 号 ]:
1005036-73-6

[ 中文名 ]:
杀真菌剂A

[ 英文名 ]:
(Rac)-Golgicide A

[英文别名 ]:

(Rac)-Golgicide A生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

[参考文献]

[1]. Sáenz JB, et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol. 2009 Mar;5(3):157-65.

[2]. van der Linden L, et al. Differential effects of the putative GBF1 inhibitors Golgicide A and AG1478 on enterovirus replication. J Virol. 2010 Aug;84(15):7535-42.

(Rac)-Golgicide A物理化学性质

[ 分子式 ]:
C₁₇H₁₄F₂N₂

[ 分子量 ]:
284.30

[ 精确质量 ]:
284.11300

[ PSA ]:
24.92000

[ LogP ]:
4.32430

[ 外观性状 ]:
固体

[ 储存条件 ]:
室温

(Rac)-Golgicide AMSDS

详细MSDS(安全技术说明书)

(Rac)-Golgicide A安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

(Rac)-Golgicide A文献

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