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4-(3-膦酰基丙基)哌嗪-2-羧酸

4-(3-膦酰基丙基)哌嗪-2-羧酸用途

(RS)-CPP((±)-CPP)是一种强效选择性NMDA拮抗剂。(RS)-CPP抑制中枢神经元反应,具有抗惊厥活性[1]。

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4-(3-膦酰基丙基)哌嗪-2-羧酸名称

[ CAS 号 ]:
100828-16-8

[ 中文名 ]:
(±)-CPP

[ 英文名 ]:
(+/-)-2-HYDROXYTRIDECANOICACID

[中文别名 ]:

[英文别名 ]:

3-2-Cpp
DL-CPP

4-(3-膦酰基丙基)哌嗪-2-羧酸生物活性

[ 描述 ]:

(RS)-CPP((±)-CPP)是一种强效选择性NMDA拮抗剂。(RS)-CPP抑制中枢神经元反应,具有抗惊厥活性[1]。

[ 相关类别 ]:

信号通路 >> 神经信号通路 >> iGluR

研究领域 >> 神经疾病

信号通路 >> 跨膜转运 >> iGluR

[参考文献]

[1]. J Davies, et al. CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity. Brain Res. 1986 Sep 10;382(1):169-73.

4-(3-膦酰基丙基)哌嗪-2-羧酸物理化学性质

[ 密度 ]:
1.408g/cm3

[ 沸点 ]:
546.7ºC at 760mmHg

[ 分子式 ]:
C₈H₁₇N₂O₅P

[ 分子量 ]:
252.20

[ 闪点 ]:
284.4ºC

[ 精确质量 ]:
252.08800

[ PSA ]:
119.91000

[ 蒸汽压 ]:
2.14E-13mmHg at 25°C

[ 折射率 ]:
1.53

[ 储存条件 ]:
室温，干燥，密封

4-(3-膦酰基丙基)哌嗪-2-羧酸MSDS

4-(3-膦酰基丙基)哌嗪-2-羧酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
22-26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

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4-(3-膦酰基丙基)哌嗪-2-羧酸文献

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