< 生产厂家价格 >

5-氯-N-(6-苯基己基)-1-萘磺酰胺

5-氯-N-(6-苯基己基)-1-萘磺酰胺用途

SC-9是在Ca2+[1][2]存在下的PKC激活剂。

点击显示

5-氯-N-(6-苯基己基)-1-萘磺酰胺名称

[ CAS 号 ]:
102649-78-5

[ 中文名 ]:
5-氯-N-(6-苯基己基)-1-萘磺酰胺

[ 英文名 ]:
SC-9

[英文别名 ]:

MFCD00065544

5-氯-N-(6-苯基己基)-1-萘磺酰胺生物活性

[ 描述 ]:

SC-9是在Ca2+[1][2]存在下的PKC激活剂。

[ 相关类别 ]:

信号通路 >> 表观遗传学 >> PKC

研究领域 >> 内分泌

信号通路 >> TGF-beta/Smad 信号通路 >> PKC

[参考文献]

[1]. Ito M, et al. N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C. Biochemistry. 1986 Jul 29;25(15):4179-84.

[2]. Nishino H, et al. N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+-activated, phospholipid-dependent protein kinase. Biochim Biophys Acta. 1986 Nov 28;889(2):236-9.

5-氯-N-(6-苯基己基)-1-萘磺酰胺物理化学性质

[ 密度 ]:
1.22g/cm3

[ 沸点 ]:
577.5ºC at 760 mmHg

[ 熔点 ]:
75-76ºC

[ 分子式 ]:
C₂₂H₂₄ClNO₂S

[ 分子量 ]:
401.94900

[ 闪点 ]:
303.1ºC

[ 精确质量 ]:
401.12200

[ PSA ]:
54.55000

[ LogP ]:
7.04630

[ 蒸汽压 ]:
2.46E-13mmHg at 25°C

[ 折射率 ]:
1.609

5-氯-N-(6-苯基己基)-1-萘磺酰胺安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2935009090

5-氯-N-(6-苯基己基)-1-萘磺酰胺海关

[ 海关编码 ]: 2935009090

[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:35.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

5-氯-N-(6-苯基己基)-1-萘磺酰胺文献

Stimulation of choline transport in cultured cells induced by 12-O-tetradecanoylphorbol-13-acetate: one of the earliest phenomena induced by the tumor promoter.

Oncology 45(4) , 326-30, (1988)

12-O-tetradecanoylphorbol-13-acetate (TPA), a potent tumor promoter, stimulated membrane transport of choline in cultured cells. This is one of the earliest phenomena caused by tumor promoter. 4-O-met...

N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+-activated, phospholipid-dependent protein kinase.

Biochim. Biophys. Acta 889 , 236, (1986)

N-(6-Phenylhexyl)-5-chloro-1-naphthalenesulfonamide (SC-9) activated Ca2+-activated, phospholipid-dependent protein kinase (protein kinase C). SC-9 acted as a substitute for phosphatidylserine, which ...

N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C.

Biochemistry 25 , 4179, (1986)

Naphthalenesulfonamide derivatives were used to study the mechanism of regulation of Ca2+-dependent smooth muscle myosin light chain phosphorylation catalyzed by Ca2+-activated, phospholipid-dependent...

更多文献