3,5-二碘-L-甲状腺素

3,5-二碘-L-甲状腺素用途

3,5-Diiodo-L-thyronine, Iodinated thyronine hormone. regulating gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.

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3,5-二碘-L-甲状腺素名称

[ CAS 号 ]:
1041-01-6

[ 中文名 ]:
3,5-二碘-L-甲状腺素

[ 英文名 ]:
3,5-Diiodo-L-thyronine

[中文别名 ]:

[英文别名 ]:

O-(4-Hydroxyphenyl)-3,5-diiodotyrosine
3,5-Diiodo-L-thyronine
Tyrosine, O-(4-hydroxyphenyl)-3,5-diiodo-
L-O-(4-hydroxyphenyl)-3,5-diiodo-Tyrosine
L-tyrosine, O-(4-hydroxyphenyl)-3,5-diiodo-
3,5-Diiodo-4-(4-hydroxyphenoxy)-L-phenylalanine
EINECS 213-867-7
L-(+)-3,5-Diiodothyronine
O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine
3,5-T2 O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine

3,5-二碘-L-甲状腺素物理化学性质

[ 密度 ]:
2.1±0.1 g/cm3

[ 沸点 ]:
559.4±50.0 °C at 760 mmHg

[ 熔点 ]:
255-260 °C (dec.)

[ 分子式 ]:
C₁₅H₁₃I₂NO₄

[ 分子量 ]:
525.077

[ 闪点 ]:
292.1±30.1 °C

[ 精确质量 ]:
524.893372

[ PSA ]:
92.78000

[ LogP ]:
3.78

[ 外观性状 ]:
灰白色固体

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.726

[ 储存条件 ]:
2-8°C

3,5-二碘-L-甲状腺素MSDS

3,5-二碘-L-甲状腺素安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922509090

3,5-二碘-L-甲状腺素合成路线

3,5-二碘-L-甲状腺素上下游产品

3,5-二碘-L-甲状腺素上游产品

3,5-二碘-L-甲状腺素下游产品

3,5-二碘-L-甲状腺素海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

3,5-二碘-L-甲状腺素文献

Administration of 3,5-diiodothyronine (3,5-T2) causes central hypothyroidism and stimulates thyroid-sensitive tissues.

J. Endocrinol. 221(3) , 415-27, (2014)

In general, 3,5-diiodothyronine (3,5-T2) increases the resting metabolic rate and oxygen consumption, exerting short-term beneficial metabolic effects on rats subjected to a high-fat diet. Our aim was...

In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles.

Toxicol. Sci. 146 , 254-64, (2015)

As in vitro assays are increasingly used to screen chemicals for their potential to produce endocrine disrupting adverse effects, it is important to understand their predictive capacity. The potential...

Ion pair hollow fiber liquid-liquid-liquid microextraction combined with capillary electrophoresis-ultraviolet detection for the determination of thyroid hormones in human serum.

J. Chromatogr. A. 1356 , 23-31, (2014)

In this study, a novel, inexpensive, sensitive and selective analytical method that combines ion pair hollow fiber liquid-liquid-liquid microextraction (IP-HF-LLLME) with capillary electrophoresis-ult...

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