< 生产厂家 价格 >

二异丁基酮

二异丁基酮用途

【用途一】
用作有机合成中间体
【用途二】
食品用香料。主要用于配制菠萝蜜、香蕉、橙汁、鸡蛋果、热带水果、朗姆酒和康酿克酒所用香精。
【用途三】
该品主要用作有机溶剂，也可用于有机合成。能溶解乙酸纤维素、硝化纤维素、聚苯乙烯、乙烯树脂、蜡、清漆、天然树脂和生胶等。由于沸点高，蒸发速度慢，可用作硝基喷漆、乙烯树脂涂料以及其他合成树脂涂料的溶剂。也是某些药物、杀虫剂的中间体。
点击显示

二异丁基酮名称

[ CAS 号 ]:
108-83-8

[ 中文名 ]:
二异丁基甲酮

[ 英文名 ]:
2,6-Dimethyl-4-heptanone

[中文别名 ]:

[英文别名 ]:

二异丁基酮物理化学性质

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
170.3±8.0 °C at 760 mmHg

[ 熔点 ]:
-46 °C

[ 分子式 ]:
C9H18O

[ 分子量 ]:
142.239

[ 闪点 ]:
45.0±0.0 °C

[ 精确质量 ]:
142.135757

[ PSA ]:
17.07000

[ LogP ]:
2.66

[ 外观性状 ]:
透明液体

[ 蒸汽密度 ]:
4.9 (vs air)

[ 蒸汽压 ]:
1.5±0.3 mmHg at 25°C

[ 折射率 ]:
1.414

[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开储运

[ 稳定性 ]:
Stable. Flammable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
0.05 g/100 mL

二异丁基酮MSDS

详细MSDS(安全技术说明书)

二异丁基酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MJ5775000
CHEMICAL NAME :
4-Heptanone, 2,6-dimethyl-
CAS REGISTRY NUMBER :
108-83-8
BEILSTEIN REFERENCE NO. :
1743163
LAST UPDATED :
199712
DATA ITEMS CITED :
41
MOLECULAR FORMULA :
C9-H18-O
MOLECULAR WEIGHT :
142.27
WISWESSER LINE NOTATION :
1Y1&1V1Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Human
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 28,262,1946
TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,60,1949
TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/15/1971
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Human
DOSE/DURATION :
50 ppm
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - headache Gastrointestinal - nausea or vomiting
REFERENCE :
NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,23,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,23,1974
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2000 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,343,1949
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1416 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SCCUR* Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583) Volume(issue)/page/year: -,4,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,23,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
30 gm/kg/3W-I
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Liver - changes in liver weight
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571116
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
130 gm/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Endocrine - hypoglycemia Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571116
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
98 ppm/6H/9D-I
TOXIC EFFECTS :
Behavioral - fluid intake Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
TIHEEC Toxicology and Industrial Health. (Princeton Scientific Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year: 3,443,1987
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 ppm/7H/6W-I
TOXIC EFFECTS :
Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 8,377,1953
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
250 ppm/7H/6W-I
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 8,377,1953 *** REVIEWS *** ACGIH TLV-TWA 145 mg/m3 (25 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 25 ppm (150 mg/m3) DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,16,1973 OSHA PEL (Gen Indu):8H TWA 50 ppm (290 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 50 ppm (290 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 50 ppm (290 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 50 ppm (290 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 25 ppm (150 mg/m3) JAN 1993 OEL-BELGIUM:TWA 25 ppm (145 mg/m3) JAN 1993 OEL-DENMARK:TWA 25 ppm (150 mg/m3) JAN 1993 OEL-FINLAND:TWA 25 ppm (150 mg/m3);STEL 40 ppm (225 mg/m3) JAN 1993 OEL-FRANCE:TWA 25 ppm (150 mg/m3) JAN 1993 OEL-GERMANY:TWA 50 ppm (290 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 25 ppm (150 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 50 ppm (290 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 25 ppm (150 mg/m3) JAN 1993 OEL-TURKEY:TWA 50 ppm (290 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 25 ppm (150 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO DIISOBUTYL KETONE-air:10H TWA 25 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 25820 No. of Facilities: 7290 (estimated) No. of Industries: 56 No. of Occupations: 49 No. of Employees: 55554 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 25820 No. of Facilities: 6204 (estimated) No. of Industries: 66 No. of Occupations: 59 No. of Employees: 72926 (estimated) No. of Female Employees: 14857 (estimated)
点击显示

二异丁基酮安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H335

[ 警示性声明 ]:
P210-P370 + P378

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R10;R37

[ 安全声明 (欧洲) ]:
S24

[ 危险品运输编码 ]:
UN 1157 3/PG 3

[ WGK德国 ]:
1

[ RTECS号 ]:
MJ5775000

[ 包装等级 ]:
III

[ 危险类别 ]:
3

[ 海关编码 ]:
2914190090

二异丁基酮合成路线

详细合成路线

二异丁基酮上下游产品

二异丁基酮上游产品

二异丁基酮下游产品

二异丁基酮制备

由丙酮经酸催化缩合生成福尔酮，再加氢还原成二异丁基酮。

精制方法：一般用蒸馏法精制。也可以通过填有硅胶的柱子，除去醇、不饱和酮、水等之后再蒸馏。
点击显示

二异丁基酮海关

[ 海关编码 ]: 2914190090

[ 中文概述 ]:
2914190090 其他不含其他含氧基的无环酮。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914190090 other acyclic ketones without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

二异丁基酮文献

The EpiOcular Eye Irritation Test (EIT) for hazard identification and labelling of eye irritating chemicals: protocol optimisation for solid materials and the results after extended shipment.

Altern. Lab. Anim. 43 , 101-27, (2015)

The 7th Amendment to the EU Cosmetics Directive and the EU REACH Regulation have reinforced the need for in vitro ocular test methods. Validated in vitro ocular toxicity tests that can predict the hum...

Efficient hydrodeoxygenation of biomass-derived ketones over bifunctional Pt-polyoxometalate catalyst.

Chem. Commun. (Camb.) 48(57) , 7194-6, (2012)

Acidic heteropoly salt Cs(2.5)H(0.5)PW(12)O(40) doped with Pt nanoparticles is a highly active and selective catalyst for one-step hydrogenation of methyl isobutyl and diisobutyl ketones to the corres...

Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane extraction.

Anal. Chim. Acta 716 , 16-23, (2012)

A totally new concept based on electrokinetic migration was evaluated for the extraction of three biologically active peptides from human plasma. Angiotensin 2, leu-enkephalin, and endomorphin 1 migra...


更多文献

相关化工产品/化学物质：

推荐生产厂家/供应商：

公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥108.0/500ml

联系人：刘佳

产品详情：二异丁基酮

公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥需询单/1mg ￥需询单/1mg ￥需询单/1mg ￥需询单/1mg

联系人：阿拉丁李高志

产品详情：二异丁基酮

查看所有供应商请点击：

二异丁基酮供应商

热门化合物

【二异丁基酮】化源网提供二异丁基酮CAS号108-83-8，二异丁基酮MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询二异丁基酮上化源网，专业又轻松。>>电脑版：二异丁基酮

标题：二异丁基酮_MSDS_用途_密度_二异丁基酮CAS号【108-83-8】_化源网 地址：https://m.chemsrc.com/mip/cas/108-83-8_1170978.html