Moxifloxacin-d3

Moxifloxacin-d3用途

莫西沙星-d3是氘标记的莫西沙星。莫西沙星是一种口服活性8-甲氧基喹诺酮类抗生素,用于治疗急性细菌性鼻窦炎、慢性支气管炎急性细菌性加重和社区获得性肺炎。

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Moxifloxacin-d3名称

[ CAS 号 ]:
1092356-42-7

[ 英文名 ]:
Moxifloxacin-d3

Moxifloxacin-d3生物活性

[ 描述 ]:

莫西沙星-d3是氘标记的莫西沙星。莫西沙星是一种口服活性8-甲氧基喹诺酮类抗生素,用于治疗急性细菌性鼻窦炎、慢性支气管炎急性细菌性加重和社区获得性肺炎。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[体外研究]

氢、碳和其他元素的稳定重同位素已被纳入药物分子,主要作为药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注[1]。

[参考文献]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

[2]. Culley, C.M., et al., Moxifloxacin: clinical efficacy and safety. Am J Health Syst Pharm, 2001. 58(5): p. 379-88.

[3]. Grayo S, et al. Comparison of the in vitro efficacies of moxifloxacin and amoxicillin against Listeria monocytogenes. Antimicrob Agents Chemother. 2008 May;52(5):1697-702.

[4]. Balfour JA, et al. Moxifloxacin: a review of its clinical potential in the management of community-acquired respiratory tract infections. Drugs. 2000 Jan;59(1):115-39.

[5]. Ioannidis O, et al. Effect of moxifloxacin on survival, lipid peroxidation and inflammation in immunosuppressed rats with soft tissue infection caused by Stenotrophomonas maltophilia. Microbiol Immunol. 2014 Feb;58(2):96-102.

Moxifloxacin-d3物理化学性质

[ 分子式 ]:
C₂₁H₂₁D₃FN₃O₄

[ 分子量 ]:
404.45

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相关化合物

[Moxifloxacin-d3]化源网提供Moxifloxacin-d3CAS号1092356-42-7，Moxifloxacin-d3MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询Moxifloxacin-d3上化源网，专业又轻松。>>电脑版：Moxifloxacin-d3

标题：【Moxifloxacin-d3】Moxifloxacin-d3 CAS号:1092356-42-7【结构式性质活性】-化源网地址：https://m.chemsrc.com/mip/cas/1092356-42-7_1710359.html