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2-氨基-6-巯嘌呤

2-氨基-6-巯嘌呤名称

[ CAS 号 ]:
1198-47-6

[ 中文名 ]:
2-氨基-6-巯嘌呤

[ 英文名 ]:
Purine, 2-amino-6- (methylthio)-

[中文别名 ]:

2-氨基-6-甲基巯嘌呤

[英文别名 ]:

2-Amino-6-methylthiopurine
6-Methylthioguanine
6-(Methylsulfanyl)-7H-purin-2-amine
Purine, 2-amino-6- (methylthio)-
S-methylthioguanine
6-(Methylsulfanyl)-1H-purin-2-amine
2-Amino-6-methylmercaptopurine
EINECS 214-833-4
1H-Purin-2-amine, 6- (methylthio)-
6-(methylsulfanyl)-7H-purin-2-ylamine

2-氨基-6-巯嘌呤物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
622.1±58.0 °C at 760 mmHg

[ 熔点 ]:
234-237ºC

[ 分子式 ]:
C₆H₇N₅S

[ 分子量 ]:
181.218

[ 闪点 ]:
330.0±32.3 °C

[ 精确质量 ]:
181.042221

[ PSA ]:
105.78000

[ LogP ]:
0.82

[ 外观性状 ]:
灰白色结晶粉末

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.761

[ 储存条件 ]:
-20°C

2-氨基-6-巯嘌呤MSDS

2-氨基-6-巯嘌呤安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H315-H318-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
24/25-39-26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2933990090

2-氨基-6-巯嘌呤合成路线

2-氨基-6-巯嘌呤海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-氨基-6-巯嘌呤文献

Liquid Chromatography with Amperometric Detection at a Silver Based Detector for the Determination of Thiocompounds: Application to the Assay of Thiopurine Antimetabolites in Urine.

Anal. Chem. 87 , 6730-5, (2015)

A silver amperometric detector coupled to liquid chromatography (LC) was used for the determination of 6-thioguanine (6-TG) and two of its metabolites, thiouric acid (TU) and 2-amino-6-mercaptopurine ...

The syntheses and properties of tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine and O6-methylguanine.

Org. Biomol. Chem. 4(9) , 1723-9, (2006)

The syntheses of novel tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine are described. The crystal structures and pKa values of these and related O6-methylguanine analogues are rep...

Reference intervals for thiopurine S-methyltransferase activity in red blood cells using 6-thioguanine as substrate and rapid non-extraction liquid chromatography.

Ann. Clin. Biochem. 41(Pt 4) , 303-8, (2004)

Although widely used, thiopurine drugs have a narrow therapeutic index and treatment can result in life-threatening toxicity, the basis being pharmacogenetic variation in thiopurine metabolism by thio...

更多文献

2-氨基-6-巯嘌呤

2-氨基-6-巯嘌呤名称

2-氨基-6-巯嘌呤物理化学性质

2-氨基-6-巯嘌呤MSDS

详细MSDS(安全技术说明书)

2-氨基-6-巯嘌呤安全信息

2-氨基-6-巯嘌呤合成路线

详细合成路线

2-氨基-6-巯嘌呤海关

2-氨基-6-巯嘌呤文献

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