邻苯二甲酸二甲酯； 避蚊酯
邻苯二甲酸二甲酯； 避蚊酯用途
邻苯二甲酸二甲酯； 避蚊酯名称
[ CAS 号 ]:
131-11-3
[ 中文名 ]:
邻苯二甲酸二甲酯
[ 英文名 ]:
Dimethyl phthalate
[中文别名 ]:
[英文别名 ]:
- phthalic acid dimethyl ester
- Phthalic acid methyl ester
- 1,2-Benzenedicarboxylic acid, dimethyl ester
- dimethyl 4-phthalate
- Dimethyl phthalate acid ester
- dimethyl 1,2-benzendicarboxylate
- Benzene-1,2-dicarboxylic acid dimethyl ester
- Dimethyl phthalate
- EINECS 205-011-6
- MFCD00008425
邻苯二甲酸二甲酯； 避蚊酯生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
邻苯二甲酸二甲酯； 避蚊酯物理化学性质
[ 密度 ]:
1.2±0.1 g/cm3
[ 沸点 ]:
282.7±8.0 °C at 760 mmHg
[ 熔点 ]:
2 °C(lit.)
[ 分子式 ]:
C10H10O4
[ 分子量 ]:
194.184
[ 闪点 ]:
146.1±0.0 °C
[ 精确质量 ]:
194.057907
[ PSA ]:
52.60000
[ LogP ]:
1.64
[ 外观性状 ]:
透明油性液体
[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C
[ 折射率 ]:
1.515
[ 储存条件 ]:
包装完整、轻装轻放,库房通风、远离明火、高温、与氧化剂分开存放
[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases, nitrates. Sensitive to prolonged exposure to light.
[ 水溶解性 ]:
<0.1 g/100 mL at 20 ºC
邻苯二甲酸二甲酯； 避蚊酯MSDS
邻苯二甲酸二甲酯； 避蚊酯毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TI1575000
- CHEMICAL NAME :
- Phthalic acid, dimethyl ester
- CAS REGISTRY NUMBER :
- 131-11-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 57
- MOLECULAR FORMULA :
- C10-H10-O4
- MOLECULAR WEIGHT :
- 194.20
- WISWESSER LINE NOTATION :
- 1OVR BVO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6800 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - withdrawal Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3375 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6800 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - withdrawal Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6500 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >1400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 9300 mg/m3/6.5H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 4400 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >20 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2400 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- >10 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 4800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 8500 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1840 ug/kg/4H/17W-I
- TOXIC EFFECTS :
- Liver - other changes Kidney, Ureter, Bladder - other changes Blood - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 360 mL/kg/13W-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 338 mg/kg
- SEX/DURATION :
- female 5-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 338 mg/kg
- SEX/DURATION :
- female 5-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 1125 mg/kg
- SEX/DURATION :
- female 5-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 1500 mg/kg
- SEX/DURATION :
- female 3-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 40,454,1977 *** REVIEWS *** ACGIH TLV-TWA 5 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,73,1973 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 54,1,1975 TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 4,3,1973 TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),267,1985 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 5 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,91,1971 OSHA PEL (Gen Indu):8H TWA 5 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 5 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 5 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 5 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 mg/m3 JAN 1993 OEL-BELGIUM:TWA 5 mg/m3 JAN 1993 OEL-DENMARK:TWA 5 mg/m3 JAN 1993 OEL-FINLAND:TWA 5 mg/m3;STEL 10 mg/m3 JAN 1993 OEL-FRANCE:TWA 5 mg/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 5 mg/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 5 mg/m3 JAN 1993 OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993 OEL-SWEDEN:TWA 3 mg/m3;STEL 5 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 5 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 5 mg/m3;STEL 10 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO DIMETHYLPHTHALATE-air:10H TWA 5 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 59210 No. of Facilities: 2879 (estimated) No. of Industries: 38 No. of Occupations: 58 No. of Employees: 50231 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 59210 No. of Facilities: 6174 (estimated) No. of Industries: 56 No. of Occupations: 66 No. of Employees: 57908 (estimated) No. of Female Employees: 16352 (estimated)
邻苯二甲酸二甲酯； 避蚊酯安全信息
[ 符号 ]:
GHS02, GHS06, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H225-H301 + H311 + H331-H370
[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311
[ 个人防护装备 ]:
Eyeshields;Gloves
[ 危害码 (欧洲) ]:
F;T
[ 风险声明 (欧洲) ]:
R20/21/22
[ 安全声明 (欧洲) ]:
S24/25-S45-S36/37-S16-S7
[ 危险品运输编码 ]:
UN 3082
[ WGK德国 ]:
1
[ RTECS号 ]:
TI1575000
邻苯二甲酸二甲酯； 避蚊酯合成路线
邻苯二甲酸二甲酯； 避蚊酯上下游产品
邻苯二甲酸二甲酯； 避蚊酯上游产品
邻苯二甲酸二甲酯； 避蚊酯下游产品
邻苯二甲酸二甲酯； 避蚊酯制备
1、硫酸催化合成 由苯酐与过量甲醇进行常压酯化而得。过量甲醇回流带水，将600kg苯酐、450g甲醇、1050mL的浓硫酸依次投入反应锅，加热回流24h，酯化温度为甲醇回流温度。反应结束后，回收甲醇，然后用碳酸钠中和，用水洗涤，再经蒸馏即得成品。原料消耗为：苯酐750kg/t，甲醇445kg/。酯化反应式如
2、树脂催化酯化合成 D72型阳离子交换树脂使用前先用约５倍体积的盐酸水溶液［狑（HCl）＝6%～7%］浸约24h，再用去离子水冲洗树脂至pH值与所用去离子水pH值相同，然后在80℃条件下烘干。将苯酐和甲醇［狀（苯酐）∶狀（甲醇）＝1∶3］、质量分数为4%的树脂置于装有搅拌器、温度计、冷凝器、分液漏斗的四口烧瓶中搅拌，加热至110℃，反应6h时间后取样测酸值，符合要求后，停止加入甲醇，继续加热15min，冷却后滤出液体。用狑（NaOH）＝3%～4%水溶液中和至pH值7～8，静置分层，减压蒸馏，收集相应温度下的馏分，即得产品。
3. 烟草：FC，40。
邻苯二甲酸二甲酯； 避蚊酯文献
J. Chromatogr. A. 1379 , 24-33, (2015)
In this study, for the first time, a dispersive liquid-liquid microextraction technique using a ternary solvent mixture is reported. In order to extract five phthalate esters and di(2-ethylhexyl) adip...
Phthalate occurrence in rivers and tap water from central Spain.Sci. Total Environ. 500-501 , 139-46, (2014)
The aim of this study is to evaluate the presence and concentrations of the main phthalates in water from the Jarama and Manzanares rivers in the region of Madrid (RM, Central Spain), the most densely...
Growth of cedar-like Au nanoparticles coating on an etched stainless steel wire and its application for selective solid-phase microextraction.Anal. Chim. Acta 876 , 55-62, (2015)
A novel cedar-like Au nanoparticles (AuNPs) coating was fabricated on an etched stainless steel (SS) wire by direct chemical deposition and used as an efficient and unbreakable solid phase microextrac...
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公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：邻苯二甲酸二甲酯
公司名：云南西力生物技术股份有限公司
区域：昆明市盘龙区
价格：
￥需询单/5mg
联系人：郑雪平
产品详情：Dimethyl phthalate
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥478.0/5mg
￥68.0/500ml
联系人：刘佳
产品详情：邻苯二甲酸二甲酯
公司名：江苏凌一实业有限公司
区域：南京市建邺区
价格：
￥150.0/1kg
联系人：周丽
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公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥54.0/5ml
￥37.0/500ml
￥146.0/2500ml
￥434.0/10l
联系人：夏言
产品详情：[Perfemiker]邻苯二甲酸二甲酯,Standard for GC，≥99.7%(GC)
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【邻苯二甲酸二甲酯； 避蚊酯】化源网提供邻苯二甲酸二甲酯； 避蚊酯CAS号131-11-3，邻苯二甲酸二甲酯； 避蚊酯MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询邻苯二甲酸二甲酯； 避蚊酯上化源网，专业又轻松。>>电脑版：邻苯二甲酸二甲酯； 避蚊酯
标题：邻苯二甲酸二甲酯； 避蚊酯_MSDS_用途_密度_CAS号【131-11-3】_化源网 地址：https://m.chemsrc.com/mip/cas/131-11-3_28935.html