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4-甲基-5-噻唑乙醇

4-甲基-5-噻唑乙醇用途

4-甲基-5-噻唑乙醇是一种天然含硫香料化合物,是一种噻唑前体[1][2]。

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4-甲基-5-噻唑乙醇名称

[ CAS 号 ]:
137-00-8

[ 中文名 ]:
4-甲基-5-(beta-羟乙基)噻唑

[ 英文名 ]:
Sulfurol

[中文别名 ]:

[英文别名 ]:

4-Methyl-5-thiazole
5-(2-hydroxyethyl)-4-methyl-1,3-thiazole
Hemineurine
4-Methyl-5-Thiazoleethanol
5-Thiazoleethanol, 4-methyl-
4-Methylthiazol-5ylethanol
5-(β-Hydroxyethyl)-4-methylthiazole
5-(2-Hydroxyethyl)-4-methylthiazole
Sulfurol
2-(4-Methylthiazole-5-yl)ethanol

4-甲基-5-噻唑乙醇生物活性

[ 描述 ]:

4-甲基-5-噻唑乙醇是一种天然含硫香料化合物,是一种噻唑前体[1][2]。

[ 相关类别 ]:

研究领域 >> 感染

[ 靶点 ]

Microbial Metabolite

[参考文献]

[1]. Ming Yin, et al. Characterization of the Key Aroma Compounds in Dog Foods by Gas Chromatography-Mass Spectrometry, Acceptance Test, and Preference Test. J Agric Food Chem. 2020 Aug 26;68(34):9195-9204.

[2]. Ryan W Paerl, et al. Use of plankton-derived vitamin B1 precursors, especially thiazole-related precursor, by key marine picoeukaryotic phytoplankton. ISME J. 2017 Mar;11(3):753-765.

4-甲基-5-噻唑乙醇物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
272.4±0.0 °C at 760 mmHg

[ 分子式 ]:
C₆H₉NOS

[ 分子量 ]:
143.20

[ 闪点 ]:
109.7±23.2 °C

[ 精确质量 ]:
143.040482

[ PSA ]:
61.36000

[ LogP ]:
0.04

[ 外观性状 ]:
无色至淡黄色液体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.564

[ 储存条件 ]:
室温，密封

4-甲基-5-噻唑乙醇MSDS

4-甲基-5-噻唑乙醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S24/25

[ 危险品运输编码 ]:
UN3334 9

[ WGK德国 ]:
3

[ 海关编码 ]:
29341000

4-甲基-5-噻唑乙醇合成路线

4-甲基-5-噻唑乙醇上下游产品

4-甲基-5-噻唑乙醇上游产品

4-甲基-5-噻唑乙醇下游产品

4-甲基-5-噻唑乙醇制备

可用4-甲基-5-醋酸乙酯以四氢锂铝进行还原反应得到。或以α-氯代乙酰丙醇与硫代甲酰胺缩合环化，然后双氧水作用，则得到所需产物。

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4-甲基-5-噻唑乙醇海关

[ 海关编码 ]: 2934100090

[ 中文概述 ]:
2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

4-甲基-5-噻唑乙醇文献

Metabolomic profiling of Burkholderia pseudomallei using UHPLC-ESI-Q-TOF-MS reveals specific biomarkers including 4-methyl-5-thiazoleethanol and unique thiamine degradation pathway.

Cell Biosci. 5 , 26, (2015)

Burkholderia pseudomallei is an emerging pathogen that causes melioidosis, a serious and potentially fatal disease which requires prolonged antibiotics to prevent relapse. However, diagnosis of melioi...

Synthesis and odor evaluation of five new sulfur-containing ester flavor compounds from 4-ethyloctanoic acid.

Molecules 15(8) , 5104-11, (2010)

Five sulfur-containing flavor compounds were synthesized for the first time by the reaction of 4-ethyloctanoyl chloride with sulfur-containing alcohols or mercaptans. The synthesized compounds are 3-(...

Characterization of thiI, a new gene involved in thiazole biosynthesis in Salmonella typhimurium.

J. Bacteriol. 179(13) , 4399-402, (1997)

Thiamine pyrophosphate (TPP) is a required cofactor in Salmonella typhimurium that is generated de novo by the condensation of 4-amino-5-hydroxymethyl pyrimidine (HMP) pyrophosphate and 4-methyl-5-(be...

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