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UDP-GAL(UDP-半乳糖)二钠盐

UDP-GAL(UDP-半乳糖)二钠盐用途

UDP半乳糖二钠是一种单糖和P2Y14受体激动剂,EC50值为0.67μM。UDP半乳糖二钠是转移酶β-1,4半乳糖基转移酶V(B4GALT5)的底物[1][2]。

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UDP-GAL(UDP-半乳糖)二钠盐名称

[ CAS 号 ]:
137868-52-1

[ 中文名 ]:
UDP-Alpha-D半乳糖二钠盐

[ 英文名 ]:
udp-alpha-d-galactose disodium salt

[中文别名 ]:

[英文别名 ]:

MFCD00077895
UDP-Gal UDP-galactose
UDP-α-D-GALACTOSE DISODIUM SALT
UDP-Gal

UDP-GAL(UDP-半乳糖)二钠盐生物活性

[ 描述 ]:

UDP半乳糖二钠是一种单糖和P2Y14受体激动剂,EC50值为0.67μM。UDP半乳糖二钠是转移酶β-1,4半乳糖基转移酶V(B4GALT5)的底物[1][2]。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> P2Y受体

研究领域 >> 神经疾病

[ 靶点 ]

P2Y14 Receptor:0.67 μM (EC50)

[参考文献]

[1]. Ko H, et al. Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J Med Chem. 2007 May 3;50(9):2030-9.

[2]. Drabavicius G, Daelemans D. Intermedilysin cytolytic activity depends on heparan sulfates and membrane composition. PLoS Genet. 2021 Feb 12;17(2):e1009387.

UDP-GAL(UDP-半乳糖)二钠盐物理化学性质

[ 密度 ]:
1.97g/cm3

[ 分子式 ]:
C₁₅H₂₂N₂Na₂O₁₇P₂

[ 分子量 ]:
610.265

[ 闪点 ]:
27 °C

[ 精确质量 ]:
610.018921

[ PSA ]:
322.27000

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
H2O: 50 mg/mL, clear, colorless

UDP-GAL(UDP-半乳糖)二钠盐MSDS

详细MSDS(安全技术说明书)

UDP-GAL(UDP-半乳糖)二钠盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26

[ 危险品运输编码 ]:
UN 2910 7

[ WGK德国 ]:
3

[ 海关编码 ]:
29400090

UDP-GAL(UDP-半乳糖)二钠盐文献

MUCILAGE-RELATED10 Produces Galactoglucomannan That Maintains Pectin and Cellulose Architecture in Arabidopsis Seed Mucilage.

Plant Physiol. 169 , 403-20, (2015)

Plants invest a lot of their resources into the production of an extracellular matrix built of polysaccharides. While the composition of the cell wall is relatively well characterized, the functions o...

Leishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesis.

Int. J. Parasitol. 45 , 783-90, (2015)

Leishmaniases are a set of tropical and sub-tropical diseases caused by protozoan parasites of the genus Leishmania whose severity ranges from self-healing cutaneous lesions to fatal visceral infectio...

Identification of a Highly Specific Isoflavone 7-O-glucosyltransferase in the soybean (Glycine max (L.) Merr.).

Plant Cell Physiol. 56 , 1512-20, (2015)

Isoflavone conjugates [7-O-β-D-glucosides and 7-O-(6″-malonyl-β-D-glucosides) of daidzein and genistein] accumulate in soybean roots and serve as the stored precursors of isoflavones (aglycons), which...

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