1-Phenazinol,6-methoxy-, 5,10-dioxide

1-Phenazinol,6-methoxy-, 5,10-dioxide用途

粘菌素是一种由抗微生物溶杆菌OH13产生的二氮氧化物吩嗪。粘菌素对许多微生物和肿瘤细胞有毒[1]。
点击显示

1-Phenazinol,6-methoxy-, 5,10-dioxide名称

[ CAS 号 ]:
13925-12-7

[ 英文名 ]:
1-Phenazinol,6-methoxy-, 5,10-dioxide

[英文别名 ]:

1-Phenazinol,6-methoxy-, 5,10-dioxide生物活性

[ 描述 ]:

粘菌素是一种由抗微生物溶杆菌OH13产生的二氮氧化物吩嗪。粘菌素对许多微生物和肿瘤细胞有毒[1]。

[ 相关类别 ]:

研究领域 >> 癌症
信号通路 >> 其他 >> 其他

[参考文献]

[1]. Liu J, et al. Monooxygenase LaPhzX is Involved in Self-Resistance Mechanisms during the Biosynthesis of N-Oxide Phenazine Myxin. J Agric Food Chem. 2021;69(45):13524-13532.

1-Phenazinol,6-methoxy-, 5,10-dioxide物理化学性质

[ 密度 ]:
1.53g/cm3

[ 沸点 ]:
538.8ºC at 760mmHg

[ 分子式 ]:
C13H10N2O4

[ 分子量 ]:
258.23000

[ 闪点 ]:
279.7ºC

[ 精确质量 ]:
258.06400

[ PSA ]:
80.38000

[ LogP ]:
2.56420

[ 蒸汽压 ]:
1.93E-12mmHg at 25°C

[ 折射率 ]:
1.73

1-Phenazinol,6-methoxy-, 5,10-dioxide毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SG1660000
CHEMICAL NAME :
1-Phenazinol, 6-methoxy-, 5,10-dioxide
CAS REGISTRY NUMBER :
13925-12-7
BEILSTEIN REFERENCE NO. :
0622031
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C13-H10-N2-O4
MOLECULAR WEIGHT :
258.25
WISWESSER LINE NOTATION :
T C666 BN INJ BO DQ IO KO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
133 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Protozoa - Euglena gracilis
DOSE/DURATION :
10 mg/L
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 27,586,1971
点击显示

1-Phenazinol,6-methoxy-, 5,10-dioxide安全信息

[ 海关编码 ]:
2933990090

1-Phenazinol,6-methoxy-, 5,10-dioxide合成路线

1-Phenazinol,6-methoxy-, 5,10-dioxide上下游产品

1-Phenazinol,6-methoxy-, 5,10-dioxide上游产品

1-Phenazinol,6-methoxy-, 5,10-dioxide下游产品

1-Phenazinol,6-methoxy-, 5,10-dioxide海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

推荐生产厂家/供应商:

暂无推荐供应商。请联系客服获知如何成为推荐供应商。


相关化合物

[1-Phenazinol,6-methoxy-, 5,10-dioxide]化源网提供1-Phenazinol,6-methoxy-, 5,10-dioxideCAS号13925-12-7,1-Phenazinol,6-methoxy-, 5,10-dioxideMSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询1-Phenazinol,6-methoxy-, 5,10-dioxide上化源网,专业又轻松。>>电脑版:1-Phenazinol,6-methoxy-, 5,10-dioxide

标题:【1-Phenazinol,6-methoxy-, 5,10-dioxide】1-Phenazinol,6-methoxy-, 5,10-dioxide CAS号:13925-12-7【结构式 性质 活性】-化源网 地址:https://m.chemsrc.com/mip/cas/13925-12-7_86249.html