邻氨基苯甲醚
邻氨基苯甲醚用途
用作染料、香料及医药中间体
【用途二】
用作测定汞的络合指示剂，偶氮染料中间体及杀菌剂
【用途三】
可用于制取偶氮染料、冰染染料及色酚AS-OL等染料以及愈创木酚、安痢平等医药。还可制取香兰素等。
【用途四】
显微微晶分析检验氰化物。络合指示剂滴定汞。有机合成。
邻氨基苯甲醚名称
[ CAS 号 ]:
90-04-0
[ 中文名 ]:
邻甲氧基苯胺
[ 英文名 ]:
2-Anisidine
[中文别名 ]:
[英文别名 ]:
- Benzenamine, 2-methoxy-
- 2-Aminoanisole
- o-Methoxyphenylamine
- 2-Anisidine
- 2-Methoxyaniline
- 1-amino-2-methoxy-benzene
- o-Anisidine
- ORTHO ANISIDINE
- ortho-Methoxyphenylamine
- 2-methoxy-phenylamine
邻氨基苯甲醚物理化学性质
[ 密度 ]:
1.1±0.1 g/cm3
[ 沸点 ]:
225.0±0.0 °C at 760 mmHg
[ 熔点 ]:
3-6 °C(lit.)
[ 分子式 ]:
C7H9NO
[ 分子量 ]:
123.152
[ 闪点 ]:
98.9±0.0 °C
[ 精确质量 ]:
123.068413
[ PSA ]:
35.25000
[ LogP ]:
1.09
[ 外观性状 ]:
淡黄色液体，暴露在空气中变成褐色
[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C
[ 折射率 ]:
1.555
[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运
[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents, acid anhydrides, chloroformates, acids, some plastics, rubber. Air sensitive.
[ 水溶解性 ]:
13 g/L (20 ºC)
邻氨基苯甲醚MSDS
邻氨基苯甲醚毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BZ5410000
- CHEMICAL NAME :
- o-Anisidine
- CAS REGISTRY NUMBER :
- 90-04-0
- BEILSTEIN REFERENCE NO. :
- 0386210
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 46
- MOLECULAR FORMULA :
- C7-H9-N-O
- MOLECULAR WEIGHT :
- 123.17
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes Blood - normocytic anemia Blood - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 870 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes Blood - normocytic anemia Blood - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 422 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- DNA inhibition
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.5 mg/m3 (0.1 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,63,1982 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.1 ppm (0.5 mg/m3) (skin) DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,10,1973 OSHA PEL (Gen Indu):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-AUSTRIA:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 0.5 mg/m3;STEL 1.5 mg/m3;Skin;Carcinogen JAN 1993 OEL-FRANCE:TWA 0.1 ppm (0.5 mg/m3);Skin;Carcinogen JAN 1993 OEL-GERMANY:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-INDIA:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.5 mg/m3;Skin JAN 1993 OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.1 ppm (0.5 mg/m3);STEL 0.2 ppm;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO o-ANISIDINE-air:10H CA TWA 0.5 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8302 No. of Facilities: 50 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 705 (estimated)
邻氨基苯甲醚安全信息
[ 符号 ]:
GHS06, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H301-H311-H331-H341-H350
[ 警示性声明 ]:
P201-P261-P280-P301 + P310-P311
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
T:Toxic;
[ 风险声明 (欧洲) ]:
R23/24/25;R45;R68
[ 安全声明 (欧洲) ]:
S53-S45
[ 危险品运输编码 ]:
UN 2431 6.1/PG 3
[ WGK德国 ]:
3
[ RTECS号 ]:
BZ5410000
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1
[ 海关编码 ]:
2922199090
邻氨基苯甲醚合成路线
邻氨基苯甲醚上下游产品
邻氨基苯甲醚上游产品
邻氨基苯甲醚下游产品
邻氨基苯甲醚制备
1.由邻硝基苯甲醚还原而得，邻硝基苯甲醚可由邻硝基氯甲苯氧基化得到[91-23-6]，还原剂可采用硫化钠或铁粉。另外，也可由邻硝基苯酚经甲基化、还原来制取邻甲氧基苯胺。原料消耗定额：邻硝基氯苯1301kg/t、甲醇（98%）395kg/t、硫化钠（60%）1128kg/t、烧碱（96%）457kg/t。
2. 烟草：BU，14。
邻氨基苯甲醚海关
[ 海关编码 ]: 2922291000
[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
[ Summary ]:
2922291000 4-methoxyaniline。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:6.5%。General tariff:30.0%
邻氨基苯甲醚文献
Regul Toxicol Pharmacol 70 Suppl 1 , S2-14, (2014)
This publication introduces a series of six other publications describing the toxicological assessment of kretek cigarettes, i.e., cigarettes characterized primarily by the use of a significant amount...
Monoarylamines in the general population--a cross-sectional population-based study including 1004 Bavarian subjects.Int. J. Hyg. Environ. Health 212(3) , 298-309, (2009)
The population-based cross-sectional study including 1004 Bavarian volunteers aged 3 up to 84 years (median: 42 years) was aimed to quantify the internal burden of monocyclic arylamines in the general...
Redox cycling in the metabolism of the environmental pollutant and suspected human carcinogen o-anisidine by rat and rabbit hepatic microsomes.Chem. Res. Toxicol. 21(8) , 1610-21, (2008)
We investigated the ability of hepatic microsomes from rat and rabbit to metabolize 2-methoxyaniline (o-anisidine), an industrial and environmental pollutant and a bladder carcinogen for rodents. Usin...
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥95.0/100ml
￥265.0/500ml
联系人：刘佳
产品详情：邻甲氧基苯胺
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥292.0/250mg
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁李高志
产品详情：邻甲氧基苯胺
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相关化合物
【邻氨基苯甲醚】化源网提供邻氨基苯甲醚CAS号90-04-0，邻氨基苯甲醚MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询邻氨基苯甲醚上化源网，专业又轻松。>>电脑版：邻氨基苯甲醚
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