安福霉素

Amphomycin是一种抑制肽聚糖合成并阻止细胞壁发育的脂肽抗生素。氨苄霉素对耐甲氧西林金黄色葡萄球菌(MRSA)、耐万古霉素肠球菌(VRE)、耐青霉素-庆大霉素-红霉素肺炎链球菌和耐利奈唑胺奎宁司汀-达福司汀肠球菌具有强大的抗菌活性[1][2][3]。

[ 描述 ]:

[ 相关类别 ]:

[体外研究]

[体内研究]

[ 密度 ]:
1.37g/cm3

[ 沸点 ]:
1693.3ºC at 760 mmHg

[ 分子式 ]:
C₅₈H₉₁N₁₃O₂₀

[ 分子量 ]:
1290.42000

[ 闪点 ]:
977.9ºC

[ 精确质量 ]:
1289.65000

[ PSA ]:
506.84000

[ LogP ]:
0.52660

[ 蒸汽压 ]:
0mmHg at 25°C

[ 折射率 ]:
1.599

CHEMICAL IDENTIFICATION

RTECS NUMBER :

BU2100000

CHEMICAL NAME :

Amphomycin

CAS REGISTRY NUMBER :

1402-82-0

LAST UPDATED :

199109

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

500 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),317,1980

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

233 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 30,9,1963

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

178 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967 Volume(issue)/page/year: -,131,1967

公司名：上海化源生化科技有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：Amphomycin

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