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异烟碱

异烟碱用途

异烟酰胺是一种生物化学试剂,可作为生物材料或有机化合物进行生命科学相关研究。

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异烟碱名称

[ CAS 号 ]:
1453-82-3

[ 中文名 ]:
4-吡啶甲酰胺

[ 英文名 ]:
Isonicotinamide

[中文别名 ]:

[英文别名 ]:

4-Pyridine carboxamide
MFCD00006432
4-pyridinecarboximidic acid
4-Pyridinecarboxamide
EINECS 215-926-2
4-(HYDROXYIMINOMETHYL)PYRIDINE
Isonicotinamide
Pyridine-4-carboximidic acid
pyridine-4-carboxamide

异烟碱生物活性

[ 描述 ]:

异烟酰胺是一种生物化学试剂,可作为生物材料或有机化合物进行生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

异烟碱物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
334.4±15.0 °C at 760 mmHg

[ 熔点 ]:
155-157 °C(lit.)

[ 分子式 ]:
C₆H₆N₂O

[ 分子量 ]:
122.13

[ 闪点 ]:
156.0±20.4 °C

[ 精确质量 ]:
122.048012

[ PSA ]:
55.98000

[ LogP ]:
-0.28

[ 外观性状 ]:
一种圆形的白色晶体

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.570

[ 储存条件 ]:
室温

[ 水溶解性 ]:
191.7 g/L (37 ºC)

异烟碱MSDS

异烟碱毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NR9500000

CHEMICAL NAME :: Isonicotinamide

CAS REGISTRY NUMBER :: 1453-82-3

BEILSTEIN REFERENCE NO. :: 0002173

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H6-N2-O

MOLECULAR WEIGHT :: 122.14

WISWESSER LINE NOTATION :: T6NJ DVZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 20 mmol/L

REFERENCE :: JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 69,1353,1982

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异烟碱安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NR9500000

[ 海关编码 ]:
29333999

异烟碱合成路线

异烟碱上下游产品

异烟碱上游产品

异烟碱下游产品

异烟碱海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

异烟碱文献

Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma.

Br. J. Cancer 111(3) , 477-85, (2014)

Current therapies for metastatic melanoma are targeted either at cancer mutations driving growth (e.g., vemurafenib) or immune-based therapies (e.g., ipilimumab). Tumour progression also requires angi...

[Fe(CN)5(isoniazid)](3-): an iron isoniazid complex with redox behavior implicated in tuberculosis therapy.

J. Inorg. Biochem. 140 , 236-44, (2014)

Tuberculosis has re-emerged as a worldwide threat, which has motivated the development of new drugs. The antituberculosis complex Na3[Fe(CN)5(isoniazid)] (IQG607) in particular is of interest on accou...

Measuring induction times and crystal nucleation rates.

Faraday Discuss. 179 , 199-214, (2015)

A large variation is observed in induction times measured under equal conditions in 1 ml solutions. Ruling out experimental errors, this variation originates from the nucleation process. The induction...

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异烟碱