Kaliotoxin (1-37)

Kaliotoxin (1-37)用途

Kaliotoxin(1-37)是一种来自蝎的毒素。Kaliotoxin(1-37)是一种有效的钙依赖性钾通道阻断剂[1]。

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Kaliotoxin (1-37)名称

[ CAS 号 ]:
150769-72-5

[ 英文名 ]:
Kaliotoxin (1-37)

Kaliotoxin (1-37)生物活性

[ 描述 ]:

Kaliotoxin(1-37)是一种来自蝎的毒素。Kaliotoxin(1-37)是一种有效的钙依赖性钾通道阻断剂[1]。

[ 相关类别 ]:

研究领域 >> 炎症/免疫

信号通路 >> 跨膜转运 >> 钾通道

[体外研究]

Kaliotoxin(1-37)与其他蝎毒素同源,如Charybdotoxin(HY-P0191；ChTX)或伊比利亚毒素(HY-P0190；IbTX)。Kaliotoxin(1-37)参与ChTX的通道阻断[1]。

Kaliotoxin (1-37)物理化学性质

[ 分子式 ]:
C₁₆₅H₂₇₁N₅₃O₄₈S₈

[ 分子量 ]:
4018.82

Kaliotoxin (1-37)安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

Kaliotoxin (1-37)文献

Kaliotoxin, a novel peptidyl inhibitor of neuronal BK-type Ca(2+)-activated K+ channels characterized from Androctonus mauretanicus mauretanicus venom.

J. Biol. Chem. 267 , 1640, (1992)

A peptidyl inhibitor of the high conductance Ca(2+)-activated K+ channels (KCa) has been purified to homogeneity from the venom of the scorpion Androctonus mauretanicus mauretanicus. The peptide has b...

Current views on scorpion toxins specific for K+-channels.

Toxicon 43 , 865-875, (2004)

Much of our knowledge on K+-channels was elucidated using specific peptide ligands isolated from a number of venomous organisms. Recently, this field received a strong support and increased interest d...

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