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1-甲基-4-亚硝基哌嗪

1-甲基-4-亚硝基哌嗪名称

[ CAS 号 ]:
16339-07-4

[ 中文名 ]:
1-甲基-4-亚硝基哌嗪

[ 英文名 ]:
Piperazine,1-methyl-4-nitroso-

[英文别名 ]:

N-Nitrosomethylpiperazine
N-Nitroso-N'-methylpiperazine
1-Nitroso-4-methylpiperazine
N-Nitroso-N'-methylpiperazin
N-Methyl-npz
Methylpiperazinenitrosamine
N-Methylnitrosopiperazine
1-methyl-4-nitroso-piperazine
PIPERAZINE,1-METHYL-4-NITROSO
Methylnitrosopiperidine

1-甲基-4-亚硝基哌嗪物理化学性质

[ 密度 ]:
1.2g/cm3

[ 沸点 ]:
236.9ºC at 760mmHg

[ 分子式 ]:
C₅H₁₁N₃O

[ 分子量 ]:
129.16000

[ 闪点 ]:
97.1ºC

[ 精确质量 ]:
129.09000

[ PSA ]:
35.91000

[ 蒸汽压 ]:
0.0463mmHg at 25°C

[ 折射率 ]:
1.561

[ 储存条件 ]:
室温

1-甲基-4-亚硝基哌嗪毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM1780000

CHEMICAL NAME :: Piperazine, 1-methyl-4-nitroso-

CAS REGISTRY NUMBER :: 16339-07-4

BEILSTEIN REFERENCE NO. :: 0117135

LAST UPDATED :: 199612

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C5-H11-N3-O

MOLECULAR WEIGHT :: 129.19

WISWESSER LINE NOTATION :: T6N DNTJ ANO D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg/59W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20800 mg/kg/40W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11440 mg/kg/22W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 10 mmol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 37,1044,1977

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1-甲基-4-亚硝基哌嗪安全信息

[ 海关编码 ]:
2933599090

1-甲基-4-亚硝基哌嗪上下游产品

1-甲基-4-亚硝基哌嗪上游产品

1-甲基-4-亚硝基哌嗪下游产品

1-甲基-4-亚硝基哌嗪海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%