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溴螨酯

溴螨酯用途

Bromopropylate 是一种具有中等抗雄激素 (anti-androgenic) 活性的农药。
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溴螨酯名称

[ CAS 号 ]:
18181-80-1

[ 中文名 ]:
溴螨酯

[ 英文名 ]:
bromopropylate

[中文别名 ]:

[英文别名 ]:

溴螨酯生物活性

[ 描述 ]:

Bromopropylate 是一种具有中等抗雄激素 (anti-androgenic) 活性的农药。

[ 相关类别 ]:

研究领域 >> 内分泌
信号通路 >> 其他 >> 雄激素受体

[ 靶点 ]

Anti-androgenic[1]


[参考文献]

[1]. Mengmeng Ma, et al. Combined Anti-Androgenic Effects of Mixtures of Agricultural Pesticides Using in Vitro and in Silico Methods. Ecotoxicol Environ Saf. 2019 Dec 30;186:109652.

溴螨酯物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
504.5±45.0 °C at 760 mmHg

[ 熔点 ]:
77ºC

[ 分子式 ]:
C17H16Br2O3

[ 分子量 ]:
428.115

[ 闪点 ]:
258.9±28.7 °C

[ 精确质量 ]:
425.946594

[ PSA ]:
46.53000

[ LogP ]:
5.43

[ 外观性状 ]:
淡黄色晶体

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.601

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

溴螨酯MSDS

详细MSDS(安全技术说明书)

溴螨酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DD2100000
CHEMICAL NAME :
Benzilic acid, 4,4'-dibromo-, isopropyl ester
CAS REGISTRY NUMBER :
18181-80-1
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C17-H16-Br2-O3
MOLECULAR WEIGHT :
428.15
WISWESSER LINE NOTATION :
ER DXQR DE&VOY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
10200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Morphological transformation

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
125 mg/kg
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 17,407,1996 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 56,107,1975
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溴螨酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R38

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
DD2100000

[ 海关编码 ]:
2918199042

溴螨酯上下游产品

溴螨酯上游产品

溴螨酯下游产品

溴螨酯制备

由4，4'-二溴二苯基羟基乙酸与异丙醇作用制得。

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溴螨酯海关

[ 海关编码 ]: 2918199042

溴螨酯文献

Gas chromatographic determination of residues of bromopropylate and two of its degradation products in honey.

J. Assoc. Off. Anal. Chem. 67(5) , 896-901, (1984)

An analytical procedure is described for determination of residues of bromopropylate (BP) and its main degradation product 4,4'-dibromobenzophenone (BBP) in honey. The method also allows the determina...

Rapid multi-residue method for the determination of azinphos methyl, bromopropylate, chlorpyrifos, dimethoate, parathion methyl and phosalone in apricots and peaches by using negative chemical ionization ion trap technology.

J. Chromatogr. A. 996(1-2) , 181-7, (2003)

A rapid, selective and sensitive multi-residue method for the determination of six common pesticides in stone fruit samples is described. The proposed method involves the extraction of the pesticides ...

Promotion of altered hepatic foci development in rat liver, cytochrome P450 enzyme induction and inhibition of cell-cell communication by DDT and some structurally related organohalogen pesticides.

Carcinogenesis 11(8) , 1413-7, (1990)

The organochlorine pesticide 1,1'-(2,2,2-trichloroethylidene) bis(4-chlorobenzene) (DDT) and four structural analogues (bromopropylate, chlorobenzilate, dicofol and fenarimol) were investigated for th...


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价格：
￥740.9/500mg ￥411.9/250mg ￥1330.9/1g ￥2400.9/2g

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