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L-紫苏醇

L-紫苏醇用途

(S)-(−)-Perillyl alcohol 是薰衣草中的单萜类物质,抑制 Ras 的法尼基化,上调 6-磷酸甘露糖受体,诱导凋亡 (apoptosis)。具有抗癌作用。

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L-紫苏醇名称

[ CAS 号 ]:
18457-55-1

[ 中文名 ]:
(S)-(-)-紫苏醇

[ 英文名 ]:
(S)-(?)-Perillyl alcohol

[中文别名 ]:

[英文别名 ]:

tri-otolylboroxine
UNII:319R5C7293
Perilla alcohol
[4-(Prop-1-en-2-yl)cyclohex-1-en-1-yl]methanol
EINECS 208-639-9
p-Mentha-1,8-diene-7-ol
(-)-PERILLYL ALCOHOL
Perillic alcohol
1-Cyclohexene-1-methanol, 4-(1-methylethenyl)
L6UTJ A1Q DY1&U1

L-紫苏醇生物活性

[ 描述 ]:

(S)-(−)-Perillyl alcohol 是薰衣草中的单萜类物质,抑制 Ras 的法尼基化,上调 6-磷酸甘露糖受体,诱导凋亡 (apoptosis)。具有抗癌作用。

[ 相关类别 ]:

信号通路 >> 细胞凋亡 >> 细胞凋亡

研究领域 >> 癌症

[参考文献]

[1]. Liston BW, et al. Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. Cancer Res. 2003 May 15;63(10):2399-403.

L-紫苏醇物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
241.2±19.0 °C at 760 mmHg

[ 分子式 ]:
C₁₀H₁₆O

[ 分子量 ]:
152.233

[ 闪点 ]:
99.6±17.8 °C

[ 精确质量 ]:
152.120117

[ PSA ]:
20.23000

[ LogP ]:
3.30

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.491

[ 储存条件 ]:
-20°C，密闭，干燥

L-紫苏醇MSDS

详细MSDS(安全技术说明书)

L-紫苏醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R37/38

[ 安全声明 (欧洲) ]:
26-39-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
OS8395000

[ 海关编码 ]:
2906199090

L-紫苏醇海关

[ 海关编码 ]: 2906199090

[ 中文概述 ]:
2906199090. 其他环烷醇，环烯醇及环萜烯醇. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

L-紫苏醇文献

Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer.

Adv. Exp. Med. Biol. 401 , 131-6, (1996)

Perillyl alcohol is a natural product from cherries and other edible plants. Perillyl alcohol and d-limonene, a closely related dietary monoterpene, have chemotherapeutic activity against pancreatic, ...

The promise of natural products for blocking early events in skin carcinogenesis.

Cancer Prev. Res. (Phila.) 3(2) , 132-5, (2010)

This perspective on Stratton et al. (beginning on p. 160), Kowalczyk et al. (beginning on p. 170), and Katiyar et al. (beginning on p. 179) highlights the common theme of translational investigation o...

Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization.

J. Ind. Microbiol. Biotechnol. 38(9) , 1359-70, (2011)

Cell physiology is a critical factor determining the efficiency of reactions performed by microbial biocatalysts. In order to develop an efficient biotransformation procedure for the hydroxylation of ...

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