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阿糖腺苷一水合物

阿糖腺苷一水合物用途

Vidarabine monohydrate 是一种腺嘌呤阿拉伯糖苷。Vidarabine monohydrate 是一种抗病毒药,对单纯疱疹病毒 (HSV) 和水痘带状疱疹病毒有活性。

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阿糖腺苷一水合物名称

[ CAS 号 ]:
24356-66-9

[ 中文名 ]:
阿糖腺苷一水合物

[ 英文名 ]:
Vidarabine monohydrate

[中文别名 ]:

[英文别名 ]:

adenine arabinoside
9-(β-D-Arabinofuranosyl)adenine Monohydrate
Arasena-A
9b-D-Arabinofuranosyladenine Monohydrate
9-(β-D-Arabinofuranosyl)-9H-purin-6-amine hydrate
spongoadenosine
6-amino-purine-7-carboxylic acid benzyl ester
Vira ATM
Ara-A Monohydrate
9-(β-D-Arabinofuranosyl)-9H-purin-6-aminhydrat

阿糖腺苷一水合物生物活性

[ 描述 ]:

Vidarabine monohydrate 是一种腺嘌呤阿拉伯糖苷。Vidarabine monohydrate 是一种抗病毒药,对单纯疱疹病毒 (HSV) 和水痘带状疱疹病毒有活性。

[ 相关类别 ]:

信号通路 >> 抗感染 >> HSV

研究领域 >> 感染

[参考文献]

[1]. Whitley, R., et al., Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs, 1980. 20(4): p. 267-82.

阿糖腺苷一水合物物理化学性质

[ 熔点 ]:
257.0-257.5ºC (0.4 H2O)

[ 分子式 ]:
C₁₀H₁₅N₅O₅

[ 分子量 ]:
285.257

[ 精确质量 ]:
285.107330

[ PSA ]:
148.77000

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 储存条件 ]:
存放于惰性气体之中;避免空气

[ 水溶解性 ]:
可溶于：二甲基甲酰胺

阿糖腺苷一水合物MSDS

详细MSDS(安全技术说明书)

阿糖腺苷一水合物毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU6210000

CHEMICAL NAME :: Adenine, 9-beta-D-arabinofuranosyl-, monohydrate

CAS REGISTRY NUMBER :: 24356-66-9

LAST UPDATED :: 199703

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H13-N5-O4.H2-O

MOLECULAR WEIGHT :: 285.30

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ IZ D- ET5OTJ B1Q CQ DQ &QH *D-ARABINO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >7950 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI) 1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year: -,180,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4677 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - peritonitis

REFERENCE :: AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI) 1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year: -,180,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2367 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 454 (estimated) No. of Female Employees: 230 (estimated)

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阿糖腺苷一水合物安全信息

[ 危害码 (欧洲) ]:
Xi

[ 海关编码 ]:
2934999090

阿糖腺苷一水合物海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%