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2-(2-羟基-5-苯甲基)苯并三唑

2-(2-羟基-5-苯甲基)苯并三唑用途

屈美唑是一种化妆品成分,具有紫外线吸收剂的作用。在急性口服、吸入或皮肤毒性研究中,屈美唑没有明显毒性[1]。

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2-(2-羟基-5-苯甲基)苯并三唑名称

[ CAS 号 ]:
2440-22-4

[ 中文名 ]:
2-(2H-苯并三氮唑-2-基)对甲苯酚

[ 英文名 ]:
Drometrizole

[中文别名 ]:

[英文别名 ]:

4-methyl-6-benzotriazol-2-yl-phenol
tinp
UV-P
Porex P
MFCD00022903
2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-methylphenol
2-(2-Hydroxy-5-Methylphenyl)benzotriazole
2,6-PYRIDINECARBOXALDEHYDE
Uvazol P
Ultraviolet Absorbent UV-P

2-(2-羟基-5-苯甲基)苯并三唑生物活性

[ 描述 ]:

屈美唑是一种化妆品成分,具有紫外线吸收剂的作用。在急性口服、吸入或皮肤毒性研究中,屈美唑没有明显毒性[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Lee JK, et al. Risk Assessment of Drometrizole, a Cosmetic Ingredient used as an Ultraviolet Light Absorber. Toxicol Res. 2019;35(2):119-129.

2-(2-羟基-5-苯甲基)苯并三唑物理化学性质

[ 密度 ]:
1.38

[ 沸点 ]:
276.1ºC at 760mmHg

[ 熔点 ]:
125.5-129.5 °C(lit.)

[ 分子式 ]:
C₁₃H₁₁N₃O

[ 分子量 ]:
225.24600

[ 闪点 ]:
133.9ºC

[ 精确质量 ]:
225.09000

[ PSA ]:
50.94000

[ LogP ]:
2.43450

[ 蒸汽压 ]:
4.81E-07mmHg at 25°C

[ 折射率 ]:
1.765

[ 储存条件 ]:
室温，干燥

2-(2-羟基-5-苯甲基)苯并三唑MSDS

详细MSDS(安全技术说明书)

2-(2-羟基-5-苯甲基)苯并三唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GO6860000

CHEMICAL NAME :: p-Cresol, 2-(2H-benzotriazol-2-yl)-

CAS REGISTRY NUMBER :: 2440-22-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C13-H11-N3-O

MOLECULAR WEIGHT :: 225.27

WISWESSER LINE NOTATION :: T56 BNNNJ CR BQ E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,835,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 10(3),49,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9391 No. of Facilities: 2261 (estimated) No. of Industries: 23 No. of Occupations: 37 No. of Employees: 52370 (estimated) No. of Female Employees: 21694 (estimated)

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2-(2-羟基-5-苯甲基)苯并三唑安全信息

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25

[ WGK德国 ]:
1

[ RTECS号 ]:
GO6860000

[ 海关编码 ]:
2933990090

2-(2-羟基-5-苯甲基)苯并三唑合成路线

详细合成路线

2-(2-羟基-5-苯甲基)苯并三唑上下游产品

2-(2-羟基-5-苯甲基)苯并三唑上游产品

2-(2-羟基-5-苯甲基)苯并三唑下游产品

2-(2-羟基-5-苯甲基)苯并三唑海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%