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富马酸单乙酯

富马酸单乙酯用途

Monoethyl fumarate 是富马酸的单乙酯形式。Monoethyl fumarate 是一种有效的高分子材料的防腐剂和聚合剂。

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富马酸单乙酯名称

[ CAS 号 ]:
2459-05-4

[ 中文名 ]:
富马酸单乙酯

[ 英文名 ]:
Monoethyl fumarate

[中文别名 ]:

反丁烯二酸二乙酯

[英文别名 ]:

Ethyl fumaric acid
2-Butenedioic acid, monoethyl ester, (2E)-
ETHYL ACID FUMARATE
Fumaric acid monoethyl ester
Monoethyl FuMerate
Ethyl fumarate
mono-Ethyl Fumarate
(2E)-4-Ethoxy-4-oxo-2-butenoic acid
RARECHEM AL BE 1505
Ethyl Hydrogen Fumarate

富马酸单乙酯生物活性

[ 描述 ]:

Monoethyl fumarate 是富马酸的单乙酯形式。Monoethyl fumarate 是一种有效的高分子材料的防腐剂和聚合剂。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Ausama Atwan, et al. Oral Fumaric Acid Esters for Psoriasis. Cochrane Database Syst Rev. 2015 Aug 10;2015(8):CD010497.

富马酸单乙酯物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
147 ºC (16 mmHg)

[ 熔点 ]:
64-69 ºC

[ 分子式 ]:
C₆H₈O₄

[ 分子量 ]:
144.125

[ 闪点 ]:
109.6±16.1 °C

[ 精确质量 ]:
144.042252

[ PSA ]:
63.60000

[ LogP ]:
0.29

[ 外观性状 ]:
近乎于白色至米色晶体粉末

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.469

[ 储存条件 ]:
Refrigerator

富马酸单乙酯MSDS

富马酸单乙酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ 海关编码 ]:
2918990090

富马酸单乙酯合成路线

富马酸单乙酯上下游产品

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富马酸单乙酯下游产品

富马酸单乙酯海关

[ 海关编码 ]: 2918990090

[ 中文概述 ]:
2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

富马酸单乙酯文献

Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).

Bioorg. Med. Chem. Lett. 21 , 2736-9, (2011)

Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids ...

Fumarate analogs act as allosteric inhibitors of the human mitochondrial NAD(P)+-dependent malic enzyme.

PLoS ONE 9(6) , e98385, (2014)

Human mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME) is allosterically activated by the four-carbon trans dicarboxylic acid, fumarate. Previous studies have suggested that the dicarboxylic...

The use of differential transverse relaxation to detect mobile species in solids.

Solid State Nucl. Magn. Reson. 6(1) , 63-71, (1996)

Delayed acquisition of the proton NMR in selected organic molecular solids (L-alanine, durene, ethyl fumarate, and p-hydroxybenzoic acid) is shown to allow the observation of mobile species in the pre...

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