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tetranor-PGEM

tetranor-PGEM用途

前列腺素E-M是前列腺素E2(PEG2)的代谢产物,是炎症和癌症的生物标志物,包括晚期结直肠癌、卵巢癌、前列腺癌等。尿中前列腺素E-M与肥胖、吸烟和乳腺癌肺转移呈正相关[1][2][3]。

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tetranor-PGEM名称

[ CAS 号 ]:
24769-56-0

[ 中文名 ]:
tetranor-PGEM

[ 英文名 ]:
tetranor-PGEM (tetranor-Prostaglandin E Metabolite)

[英文别名 ]:

TETRANOR-PGEM
tetranor-prostaglandin E metabolite
tetranor-PGEM Lipid Maps MS Standard

tetranor-PGEM生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

研究领域 >> 炎症/免疫

[参考文献]

[1]. Johnson JC, et al. Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin Gastroenterol Hepatol. 2006 Nov;4(11):1358-65.

[2]. Wang D, DuBois RN. Urinary PGE-M: a promising cancer biomarker. Cancer Prev Res (Phila). 2013 Jun;6(6):507-10.

[3]. Morris PG, et al. Increased levels of urinary PGE-M, a biomarker of inflammation, occur in association with obesity, aging, and lung metastases in patients with breast cancer. Cancer Prev Res (Phila). 2013 May;6(5):428-36.

tetranor-PGEM物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
622.4±55.0 °C at 760 mmHg

[ 分子式 ]:
C₁₆H₂₄O₇

[ 分子量 ]:
328.358

[ 闪点 ]:
344.2±28.0 °C

[ 精确质量 ]:
328.152191

[ PSA ]:
128.97000

[ LogP ]:
-0.90

[ 蒸汽压 ]:
0.0±4.1 mmHg at 25°C

[ 折射率 ]:
1.529

[ 储存条件 ]:
-20°C，密闭，干燥

tetranor-PGEM安全信息

[ 海关编码 ]:
2918990090

tetranor-PGEM海关

[ 海关编码 ]: 2918990090

[ 中文概述 ]:
2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%