2-甲基-4-异噻唑啉-3-酮盐酸盐

2-甲基-4-异噻唑啉-3-酮盐酸盐用途

Methylisothiazolinone hydrochloride 是杀生物剂 Kathon CG 的成分,是一种广泛用作防腐剂的异噻唑酮衍生物。Methylisothiazolinone hydrochloride 也是一种中等敏化剂,可与 GSH 反应。

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2-甲基-4-异噻唑啉-3-酮盐酸盐名称

[ CAS 号 ]:
26172-54-3

[ 中文名 ]:
2-甲基-4-异噻唑啉-3-酮盐酸盐

[ 英文名 ]:
Methylisothiazolinone hydrochloride

[中文别名 ]:

2-甲基-3(2H)-异噻唑酮盐酸盐

[英文别名 ]:

2-Methyl-3-isothiazoloneHydrochloride
MIT,Methylisothiazolinone hydrochloride
2-methyl-1,2-thiazol-3-one,hydrochloride
EINECS 247-499-3
MFCD06804636

2-甲基-4-异噻唑啉-3-酮盐酸盐生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. Rubén Alvarez-Sánchez, et al. Covalent Binding of the 13C-labeled Skin Sensitizers 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisothiazol-3-one (MI) to a Model Peptide and Glutathione. Bioorg Med Chem Lett. 2004 Jan 19;14(2):365-8.

[2]. Aynur O Aptula, et al. From Experiment to Theory: Molecular Orbital Parameters to Interpret the Skin Sensitization Potential of 5-chloro-2-methylisothiazol-3-one and 2-methylisothiazol-3-one. Chem Res Toxicol. 2005 Feb;18(2):324-9.

2-甲基-4-异噻唑啉-3-酮盐酸盐物理化学性质

[ 分子式 ]:
C₄H₆ClNOS

[ 分子量 ]:
151.61500

[ 精确质量 ]:
150.98600

[ PSA ]:
50.24000

[ LogP ]:
1.24880

[ 外观性状 ]:
白色到类白色粉末

[ 储存条件 ]:
2-8°C

2-甲基-4-异噻唑啉-3-酮盐酸盐MSDS

2-甲基-4-异噻唑啉-3-酮盐酸盐安全信息

[ 符号 ]:

GHS05, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314-H317-H334

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C

[ 风险声明 (欧洲) ]:
34-42/43

[ 安全声明 (欧洲) ]:
26-36/37/39-45

[ 危险品运输编码 ]:
UN 1759 8/PG 2

[ WGK德国 ]:
3

[ 海关编码 ]:
2934999090

2-甲基-4-异噻唑啉-3-酮盐酸盐合成路线

2-甲基-4-异噻唑啉-3-酮盐酸盐上下游产品

2-甲基-4-异噻唑啉-3-酮盐酸盐上游产品

2-甲基-4-异噻唑啉-3-酮盐酸盐下游产品

2-甲基-4-异噻唑啉-3-酮盐酸盐海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-甲基-4-异噻唑啉-3-酮盐酸盐文献

Methylisothiazolinone contact allergy and dose-response relationships.

Contact Dermatitis 64(6) , 330-6, (2011)

Methylisothiazolinone (MI) used alone is a new preservative causing a high prevalence of contact allergy. The eliciting threshold of MI is unknown. The combination of MI and phenoxyethanol enhances th...

Biocide immobilized OMMT-carbon dot reduced Cu2O nanohybrid/hyperbranched epoxy nanocomposites: Mechanical, thermal, antimicrobial and optical properties.

Mater. Sci. Eng. C. Mater. Biol. Appl. 56 , 74-83, (2015)

The present work demonstrated a transparent thermosetting nanocomposite with antimicrobial and photoluminescence attributes. The nanocomposites are fabricated by incorporation of different wt.% (1, 2 ...

Follow-up of the monitored levels of preservative sensitivity in Europe: overview of the years 2001-2008.

Contact Dermatitis 67(5) , 312-4, (2012)

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