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3-巯基异丁酸

3-巯基异丁酸用途

Captopril EP Impurity C 是一种 Captopril 的杂质。Captopril 是一种含巯基的口服活性血管紧张素转换酶 (ACE) 抑制剂 (IC50=0.025 μM)。

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3-巯基异丁酸名称

[ CAS 号 ]:
26473-47-2

[ 中文名 ]:
3-巯基异丁酸

[ 英文名 ]:
Captopril EP Impurity C

[英文别名 ]:

Captopril impurity C
EINECS 247-726-6
Propanoic acid, 3-mercapto-2-methyl-
3-sulfhydryl isobutyric acid
3-mercapto-2-methylpropionic acid
3-mercapto-2-methylpropanoic acid
3-Mercaptoisobutyric acid
MFCD00671555
UNII:V3E4016VAS
3-Mercapto-2-methyl propanoic acid

3-巯基异丁酸生物活性

[ 描述 ]:

Captopril EP Impurity C 是一种 Captopril 的杂质。Captopril 是一种含巯基的口服活性血管紧张素转换酶 (ACE) 抑制剂 (IC50=0.025 μM)。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. ANCA GABRIELA CÂRJE, et al. HPLC-UV METHOD APPROACH FOR THE ANALYSIS AND IMPURITY PROFILING OF CAPTOPRIL.

[2]. Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64(11):2263-2268.

[3]. Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35.

3-巯基异丁酸物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
232.5±23.0 °C at 760 mmHg

[ 分子式 ]:
C₄H₈O₂S

[ 分子量 ]:
120.170

[ 闪点 ]:
94.4±22.6 °C

[ 精确质量 ]:
120.024498

[ PSA ]:
76.10000

[ LogP ]:
0.78

[ 外观性状 ]:
液体;Colorless to Light yellow to Light orange clear liquid

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.491

[ 储存条件 ]:
室温，干燥

3-巯基异丁酸MSDS

详细MSDS(安全技术说明书)

3-巯基异丁酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2930909090

3-巯基异丁酸上下游产品

3-巯基异丁酸上游产品

3-巯基异丁酸下游产品

3-巯基异丁酸海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

3-巯基异丁酸文献

The utilization of 3-mercapto-2-methylpropionate as sulphur source by a phototrophic bacterium.

Bioorg. Med. Chem. 2(7) , 589-93, (1994)

A bacterium (strain photoB) photoassimilated 3-mercapto-2-methylpropionate as sole source of sulphur with methacrylate accumulating in the medium. This was thought to be the product of a sulphur-lyase...

Bacterial taxa that limit sulfur flux from the ocean.

Science 314(5799) , 649-52, (2006)

Flux of dimethylsulfide (DMS) from ocean surface waters is the predominant natural source of sulfur to the atmosphere and influences climate by aerosol formation. Marine bacterioplankton regulate sulf...

Methylthiol:coenzyme M methyltransferase from Methanosarcina barkeri, an enzyme of methanogenesis from dimethylsulfide and methylmercaptopropionate.

J. Bacteriol. 179(22) , 6902-11, (1997)

During growth on acetate, Methanosarcina barkeri expresses catabolic enzymes for other methanogenic substrates such as monomethylamine. The range of substrates used by cells grown on acetate was furth...

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